Evidence map›Paper›PMID 33692672›Full record

ArticleFrontiers in neuroscience2021

Language Dysfunction in Schizophrenia: Assessing Neural Tracking to Characterize the Underlying Disorder(s)?

Lars Meyer, Peter Lakatos, Yifei He

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. The neocortical infrastructure for language involves region-specific patterns of laminar gene expression.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Perceptual Functioning.Current topics in behavioral neurosciences · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lars MeyerResearch Group Language Cycles, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Peter LakatosCenter for Biomedical Imaging and Neuromodulation, Nathan Kline Institute, Orangeburg, NY, United States.
Yifei HeDepartment of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany.

Funding

Project 5: ComputationalP50MH109429 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI Robert Thomas Knight · 2017 to 2026
$25.3M
Cortical and thalamic mechanisms of selective auditory attentionR01DC012947 · NIDCD · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI NEYMOTIN, SAMUEL A, SCHROEDER, CHARLES E · 2013 to 2022
$5.2M
Temporal dynamics of neurophysiological patterns as treatment targets in SzR01MH109289 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI JAVITT, DANIEL C. · 2016 to 2020
$3.7M
NIDCD NIH HHS R01 DC012947NIMH NIH HHS P50 MH109429NIMH NIH HHS R01 MH109289
6 · The paper itself

Abstract

Deficits in language production and comprehension are characteristic of schizophrenia. To date, it remains unclear whether these deficits arise from dysfunctional linguistic knowledge, or dysfunctional predictions derived from the linguistic context. Alternatively, the deficits could be a result of dysfunctional neural tracking of auditory information resulting in decreased auditory information fidelity and even distorted information. Here, we discuss possible ways for clinical neuroscientists to employ neural tracking methodology to independently characterize deficiencies on the auditory-sensory and abstract linguistic levels. This might lead to a mechanistic understanding of the deficits underlying language related disorder(s) in schizophrenia. We propose to combine naturalistic stimulation, measures of speech-brain synchronization, and computational modeling of abstract linguistic knowledge and predictions. These independent but likely interacting assessments may be exploited for an objective and differential diagnosis of schizophrenia, as well as a better understanding of the disorder on the functional level-illustrating the potential of neural tracking methodology as translational tool in a range of psychotic populations.

Indexed as

electroencephalographylanguage comprehensionneural oscillationsneural trackingschizophreniaspeech perception

Identifiers

PMID33692672
PMCPMC7937925

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.