Evidence map›Paper›PMID 33692492›Full record

ArticleCell research2021

Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans.

Xin-Xin Yu, Wei-Lin Qiu, Liu Yang, Yan-Chun Wang, Mao-Yang He, Dan Wang, Yu Zhang, Lin-Chen Li, Jing Zhang, Yi Wang and 1 more

Open access · greenAbstract read
In one paragraph

Article in Cell research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Charting Endocrine Progenitors Across Species and Organs.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Article
  5. Novel concepts of cell-of origin in neuroendocrine neoplasms.Virchows Archiv : an international journal of pathology · 2026
    Review
  6. Article
  7. Differentiation Stage Predicts Radiosensitivity in Mesenchymal-Like Pancreatic Cancer.International journal of radiation oncology, biology, physics · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Molecular Basis of Pancreatic Neuroendocrine Tumors.International journal of molecular sciences · 2024
    Review
  16. β-Cell Heterogeneity and Plasticity.Advances in anatomy, embryology, and cell biology · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xin-Xin Yu *Department of Human Anatomy, Histology, and Embryology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China.
Wei-Lin Qiu *Department of Human Anatomy, Histology, and Embryology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China.ORCID http://orcid.org/0000-0002-6649-0378
Liu Yang *Department of Human Anatomy, Histology, and Embryology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China.
Yan-Chun Wang *Haidian Maternal & Child Health Hospital, Beijing, 100080, China.
Mao-Yang HeMinistry of Education Key Laboratory of Cell Proliferation and Differentiation, College of Life Sciences, Peking University, Beijing, 100871, China.
Dan WangDepartment of Human Anatomy, Histology, and Embryology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China.
Yu ZhangDepartment of Human Anatomy, Histology, and Embryology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China.
Lin-Chen LiPeking-Tsinghua Center for Life Sciences, Peking University, Beijing, 100871, China.
Jing ZhangHaidian Maternal & Child Health Hospital, Beijing, 100080, China.
Yi WangHaidian Maternal & Child Health Hospital, Beijing, 100080, China.
Cheng-Ran XuDepartment of Human Anatomy, Histology, and Embryology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China. cxu@pku.edu.cn.ORCID http://orcid.org/0000-0002-0583-4464
Peking University · CNHainan Maternal and Child Health Hospital · CN

Funding

China Postdoctoral Science Foundation 2020TQ0018China Postdoctoral Science Foundation BX20190009Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) 2015CB942800Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) 2019YFA0801500National Natural Science Foundation of China (National Science Foundation of China) 31521004National Natural Science Foundation of China (National Science Foundation of China) 32030034National Natural Science Foundation of China (National Science Foundation of China) 91753138
6 · The paper itself

Abstract

The pancreatic islet contains multiple hormone

Indexed as

Islets of LangerhansPancreasAnimalsCell DifferentiationCell LineageHumansMiceStem Cells

Identifiers

PMID33692492
PMCPMC8324815
OpenAlexW3133489489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.