ArticleScientific reports2021
A multicenter study of interocular symmetry of corneal biometrics in Chinese myopic patients.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Interocular agreement and differences of ocular growth in cataract patients.Scientific reports · 2026Article
- Central corneal thickness, corneal endothelial cell density, and morphology in myopic eyes of young Chinese candidates for refractive surgery.Frontiers in ophthalmology · 2026Article
- Quantifying posterior corneal astigmatism's contribution to ocular residual astigmatism: implications for personalized refractive surgery.International ophthalmology · 2025Article
- Prevalence of interocular symmetry in corneal astigmatism and the possible influence of age, sex and refractive error.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Article
- Correlations of anterior and posterior corneal parameters in Chinese myopic patients: a retrospective multicenter study.Quantitative imaging in medicine and surgery · 2025Article
- Interocular symmetry and asymmetry in ocular health and disease.Frontiers in medicine · 2025Review
- Ocular biometric parameters among Han and Uyghur young adults with myopia in Xinjiang, China.International journal of ophthalmology · 2025Article
- Enhanced morphological assessment based on interocular asymmetry analysis for keratoconus detection.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Ocular biometrics in eyes with different white-to-white corneal diameter in young myopic adults.Scientific reports · 2024Article
- When Sex Matters: Differences in the Central Nervous System as Imaged by OCT through the Retina.Journal of imaging · 2023Article
- The application of corneal biomechanical interocular asymmetry for the diagnosis of keratoconus and subclinical keratoconus.Frontiers in bioengineering and biotechnology · 2023Article
- Survival analysis of myopic regression after small incision lenticule extraction and femtosecond laser-assisted laser in situ keratomileusis for low to moderate myopia.Eye and vision (London, England) · 2022Article
- Quantitative interocular comparison of total corneal surface area and corneal diameter in patients with highly asymmetric keratoconus.Scientific reports · 2022Article
- The Distribution Pattern of Ocular Residual Astigmatism in Chinese Myopic Patients.Frontiers in medicine · 2022Article
- Interocular Symmetry Analysis of Corneal Elevation Using the Fellow Eye as the Reference Surface and Machine Learning.Healthcare (Basel, Switzerland) · 2021Article
- A Multicenter Study of the Distribution Pattern of Posterior-To-Anterior Corneal Curvature Radii Ratio in Chinese Myopic Patients.Frontiers in medicine · 2021Article
- Distribution of White-to-White Corneal Diameter and Anterior Chamber Depth in Chinese Myopic Patients.Frontiers in medicine · 2021Article
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Authors and funding
14 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is essential to know the normal range of the interocular symmetry of the cornea (ISC) for keratoconus diagnosis and corneal substitutes design. In the present study we investigated the interocular symmetry of corneal biometrics in 6,644 Chinese myopic patients from multiple ophthalmic centers. Corneal biometrics of both eyes were exported from the Pentacam instrument. Interocular symmetry of the corneal biometrics was analyzed by Spearman's correlation test, intraclass correlation coefficient (ICC) analysis and Bland-Altman plot. Significantly strong interocular correlations were found in anterior and posterior corneal curvatures, corneal diameter, corneal thickness, corneal volume, corneal eccentricity, and corneal asphericity (r = 0.87-0.98, all P < 0.001). Moderate interocular correlations were observed in whole corneal astigmatism (r = 0.78) and posterior corneal astigmatism (r = 0.73). ICC between the right and left eyes was 0.94-0.98 for anterior and posterior corneal curvatures, corneal diameter, corneal thickness and corneal volume, 0.80-0.88 for corneal eccentricity and asphericity, and 0.73-0.79 for corneal astigmatism (all P < 0.001). Bland-Altman plot showed that the 95% limit of agreement between both eyes was narrow and symmetric in most of the corneal biometrics, suggesting strong interocular agreements in these corneal biometrics. In conclusion, significant interocular symmetry of corneal biometrics is observed in Chinese myopia patients. Extra attention should be paid to patients with interocular corneal asymmetry.
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