Evidence map›Paper›PMID 33692231›Full record

ArticleThe Journal of veterinary medical science2021

Presumptive hemophagocytic syndrome associated with immune-mediated anemia in two Miniature Dachshunds.

Makoto Akiyoshi, Masaharu Hisasue, Sakurako Neo, Masami Akiyoshi

Open access · diamondAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Makoto AkiyoshiLaboratory of Small Animal Internal Medicine, Azabu University, Sagamihara-shi, 1-17-71 Fuchinobe, Chuuku, Sagamihara-shi, Kanagawa 252-5201, Japan.
Masaharu HisasueLaboratory of Small Animal Internal Medicine, Azabu University, Sagamihara-shi, 1-17-71 Fuchinobe, Chuuku, Sagamihara-shi, Kanagawa 252-5201, Japan.
Sakurako NeoLaboratory of Clinical Diagnosis, Azabu University, 1-17-71 Fuchinobe, Chuoku, Sagamihara-shi, Kanagawa 252-5201, Japan.
Masami AkiyoshiAkiyoshi Animal Clinic, 5-4-26 Chuorinkannishi, Yamato-shi, Kanagawa 242-0008, Japan.
Azabu University · JPObayashi (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report describes the cases of two Miniature Dachshunds who were suspected to have immune-mediated hemolytic anemia (IMHA) and were treated with immunosuppressive therapy. However, progression of anemia, increases in C-reactive protein (CRP) and total-bilirubin (T-Bil) levels, splenomegaly, transition to nonregenerative anemia, and thrombocytopenia occurred after the treatment. Splenectomy and bone-marrow aspirations were performed subsequently. Both dogs were diagnosed with hemophagocytic syndrome (HPS) associated with IMHA. Unfortunately, they died 9 and 6 days later. These findings indicate that some cases of refractory IMHA have the pathogenicity of HPS. HPS should be included as a differential diagnosis of refractory IMHA concurrent with thrombocytopenia. Continuously elevated CRP and T-Bil levels may be helpful indicators in the detection of HPS associated with IMHA.

Indexed as

Anemia, Hemolytic, AutoimmuneDog DiseasesLymphohistiocytosis, HemophagocyticThrombocytopeniaAnimalsDogsSplenectomyautoimmune-associated hemophagocytic syndromeevans’ syndromehemophagocytosisimmune-mediated hemolytic anemiathrombocytopenia

Identifiers

PMID33692231
PMCPMC8111343
OpenAlexW3134233873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.