Evidence map›Paper›PMID 33692198›Full record

ArticlemSphere2021

Mapping Gene-by-Gene Single-Nucleotide Variation in 8,535 Mycobacterium tuberculosis Genomes: a Resource To Support Potential Vaccine and Drug Development.

Danai Papakonstantinou, Steven J Dunn, Simon J Draper, Adam F Cunningham, Matthew K O'Shea, Alan McNally

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Microbiology spectrum · 2022
    Article
  2. Gene evolutionary trajectories inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Danai PapakonstantinouInstitute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.ORCID 0000-0003-1629-6937
Steven J DunnInstitute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.ORCID 0000-0003-1529-6900
Simon J DraperJenner Institute, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-9415-1357
Adam F CunninghamInstitute of Immunology and Immunotherapy, MRC Centre of Immune Regulation, University of Birmingham, Birmingham, United Kingdom.ORCID 0000-0003-0248-964X
Matthew K O'Shea *Institute of Immunology and Immunotherapy, MRC Centre of Immune Regulation, University of Birmingham, Birmingham, United Kingdom m.k.oshea@bham.ac.uk a.mcnally.1@bham.ac.uk.ORCID 0000-0001-6414-8088
Alan McNally *Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom m.k.oshea@bham.ac.uk a.mcnally.1@bham.ac.uk.ORCID 0000-0002-3099-630X
University of Birmingham · GBImmune Regulation (United Kingdom) · GBUniversity of Oxford · GB

Funding

Medical Research Council MR/L015080/1Medical Research Council MR/T030062/1Wellcome Trust
6 · The paper itself

Abstract

Tuberculosis (TB) is responsible for millions of deaths annually. More effective vaccines and new antituberculous drugs are essential to control the disease. Numerous genomic studies have advanced our knowledge about

Indexed as

Genome, BacterialPolymorphism, Single NucleotideTuberculosis VaccinesDatasets as TopicDrug DevelopmentDrug DiscoveryHumansMycobacterium tuberculosisTuberculosisTuberculosis Vaccinesdrug targetsMycobacterium tuberculosissingle nucleotide polymorphismssingle-nucleotide variationSNPsTBtuberculosistuberculosis vaccinesvaccine candidates

Identifiers

PMID33692198
PMCPMC8546714
OpenAlexW3134642172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.