Evidence map›Paper›PMID 33691907›Full record

ReviewBMB reports2021

A novel role of Hippo-Yap/TAZ signaling pathway in lymphatic vascular development.

Boksik Cha, Sungjin Moon, Wantae Kim

Open access · goldAbstract readReview
In one paragraph

Review in BMB reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Boksik ChaDaegu Gyeongbuk Medical Innovation Foundation, Daegu 41061, Korea.
Sungjin MoonDepartment of Biological Science, Kangwon National University, Chuncheon 24341, Korea.
Wantae KimDepartment of Biochemistry, Chungnam National University, Daejeon 34134, Korea.
Chungnam National University · KRDaegu-Gyeongbuk Medical Innovation Foundation · KRKangwon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lymphatic vasculature plays important role in regulating fluid homeostasis, intestinal lipid absorption, and immune surveillance in humans. Malfunction of lymphatic vasculature leads to several human diseases. Understanding the fundamental mechanism in lymphatic vascular development not only expand our knowledge, but also provide a new therapeutic insight. Recently, Hippo-YAP/TAZ signaling pathway, a key mechanism of organ size and tissue homeostasis, has emerged as a critical player that regulate lymphatic specification, sprouting, and maturation. In this review, we discuss the mechanistic regulation and pathophysiological significant of Hippo pathway in lymphatic vascular development. [BMB Reports 2021; 54(6): 285-294].

Indexed as

Hippo Signaling PathwayLymphangiogenesisHumansLymphatic SystemTranscriptional Coactivator with PDZ-Binding Motif ProteinsYAP-Signaling ProteinsTranscriptional Coactivator with PDZ-Binding Motif ProteinsWWTR1 protein, humanYAP1 protein, humanYAP-Signaling Proteins

Identifiers

PMID33691907
PMCPMC8249877
OpenAlexW3135625230

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.