Evidence map›Paper›PMID 33691702›Full record

Trial reportRespiratory research2021

Efficacy of a long-term pulmonary rehabilitation maintenance program for COPD patients in a real-life setting: a 5-year cohort study.

Léo Blervaque, Christian Préfaut, Hélène Forthin, Francis Maffre, Marion Bourrelier, Nelly Héraud, Matthias Catteau, Pascal Pomiès, Dany Jaffuel, Nicolas Molinari and 2 more

Abstract readMulticenter StudyPragmatic Clinical Trial
In one paragraph

Trial report in Respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Léo BlervaquePhyMedExp, INSERM U1046, CNRS UMR 9214, Montpellier University, Montpellier, France.
Christian PréfautAir+R Network, Montpellier University, Montpellier, France.
Hélène ForthinAir+R Network, Montpellier, France.
Francis MaffreAir+R Network, Montpellier, France.
Marion BourrelierAir+R Network, Montpellier, France.
Nelly HéraudDirection de la recherche clinique et de l'innovation en santé - KORIAN SANTE, 34700, Lodève, France.
Matthias CatteauPhyMedExp, INSERM U1046, CNRS UMR 9214, Montpellier University, Montpellier, France.
Pascal PomièsPhyMedExp, INSERM U1046, CNRS UMR 9214, Montpellier University, Montpellier, France.
Dany JaffuelDepartment of Pneumology, Montpellier University Hospital, Montpellier, France.
Nicolas MolinariIMAG, CNRS, Montpellier University, Montpellier University Hospital, Montpellier, France.
Maurice HayotPhyMedExp, University of Montpellier, INSERM, CNRS, CHRU, Montpellier, France.
Fares GouziPhyMedExp, University of Montpellier, INSERM, CNRS, CHRU, Montpellier, France. f-gouzi@chu-montpellier.fr.ORCID http://orcid.org/0000-0001-8970-866X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary rehabilitation (PR) improves exercise capacity, health-related quality of life (HRQoL) and dyspnea in chronic obstructive pulmonary disease (COPD) patients. Maintenance programs can sustain the benefits for 12 to 24 months. Yet, the long-term effects (> 12 months) of pragmatic maintenance programs in real-life settings remain unknown. This prospective cohort study assessed the yearly evolution in the outcomes [6-min walking distance (6MWD), HRQoL, dyspnea] of a supervised self-help PR maintenance program for COPD patients followed for 5 years. The aim was to assess the change in the outcomes and survival probability for 1 to 5 years after PR program discharge in COPD patients following a PR maintenance program supported by supervised self-help associations.

methodsData were prospectively collected from 144 COPD patients who followed a pragmatic multidisciplinary PR maintenance program for 1 to 5 years. They were assessed yearly for 6MWD, HRQol (VQ11) and dyspnea (MRC). The 5-year survival probability was compared to that of a control PR group without a maintenance program. A trajectory-based cluster analysis identified the determinants of long-term response.

resultsMaintenance program patients showed significant PR benefits at 4 years for 6MWD and VQ11 and 5 years for MRC. The 5-year survival probability was higher than for PR patients without PR maintenance. Two clusters of response to long-term PR were identified, with responders being the less severe COPD patients.

conclusionsThis study provides evidence of the efficacy of a pragmatic PR maintenance program in a real-life setting for more than 3 years. In contrast to short-term PR, long-term PR maintenance appeared more beneficial in less severe COPD patients.

Indexed as

AgedCohort StudiesDatabases, FactualExercise TherapyExercise ToleranceFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesPulmonary Disease, Chronic ObstructiveSurvival RateTime FactorsCOPDMaintenance programsPulmonary rehabilitationSurvival

Identifiers

PMID33691702
PMCPMC7948332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.