Evidence map›Paper›PMID 33691355›Full record

ArticleJournal of osteopathic medicine2021

Development of atrial fibrillation following trauma increases short term risk of cardiovascular events.

Sean P Nassoiy, Robert H Blackwell, McKenzie Brown, Anai N Kothari, Timothy P Plackett, Paul C Kuo, Joseph A Posluszny

Open access · hybridAbstract read
In one paragraph

Article in Journal of osteopathic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Analysis of Global Research Trends of Trauma-Related Arrhythmias.Open access emergency medicine : OAEM · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sean P NassoiyDepartment of Surgery, One: MAP Surgical Analytics, Loyola University Medical Center, Maywood, IL, USA.
Robert H BlackwellDepartment of Surgery, One: MAP Surgical Analytics, Loyola University Medical Center, Maywood, IL, USA.
McKenzie BrownDepartment of Surgery, One: MAP Surgical Analytics, Loyola University Medical Center, Maywood, IL, USA.
Anai N KothariDepartment of Surgery, One: MAP Surgical Analytics, Loyola University Medical Center, Maywood, IL, USA.
Timothy P PlackettDepartment of Surgery, One: MAP Surgical Analytics, Loyola University Medical Center, Maywood, IL, USA.
Paul C KuoDepartment of Surgery, One: MAP Surgical Analytics, Loyola University Medical Center, Maywood, IL, USA.
Joseph A PoslusznyDepartment of Surgery, One: MAP Surgical Analytics, Loyola University Medical Center, Maywood, IL, USA.
Loyola University Medical Center · US

Funding

TRAINING IN TRAUMA AND BURN RESEARCHT32GM008750 · NIGMS · LOYOLA UNIVERSITY CHICAGO · PI CHOUDHRY, MASHKOOR A, GONZALEZ, RICHARD PAUL · 2000 to 2023
$2.9M
Basic and Clinical Research Training for Medical StudentsT35HL120835 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI ZELEZNIK-LE, NANCY J · 2015 to 2024
$628k
NHLBI NIH HHS T35 HL120835NIGMS NIH HHS T32 GM008750
6 · The paper itself

Abstract

contextNew onset atrial fibrillation (AF) is associated with poor outcomes in several different patient populations.

objectivesTo assess the effect of developing AF on cardiovascular events such as myocardial infarction (MI) and cerebrovascular accident (CVA) during the acute index hospitalization for trauma patients.

methodsThe Healthcare Cost and Utilization Project State Inpatient Databases for California and Florida were used to identify adult trauma patients (18 years of age or older) who were admitted between 2007 and 2010. After excluding patients with a history of AF and prior history of cardiovascular events, patients were evaluated for MI, CVA, and death during the index hospitalization. A secondary analysis was performed using matched propensity scoring based on age, race, and preexisting comorbidities.

resultsDuring the study period, 1,224,828 trauma patients were admitted. A total of 195,715 patients were excluded for a prior history of AF, MI, or CVA. Of the remaining patients, 15,424 (1.5%) met inclusion criteria and had new onset AF after trauma. There was an associated increase in incidence of MI (2.9 vs. 0.7%; p<0.001), CVA (2.6 vs. 0.4%; p<0.001), and inpatient mortality (8.5 vs. 2.1%; p<0.001) during the index hospitalization in patients who developed new onset AF compared with those who did not. Cox proportional hazards regression demonstrated an increased risk of MI (odds ratio [OR], 2.35 [2.13-2.60]), CVA (OR, 3.90 [3.49-4.35]), and inpatient mortality (OR, 2.83 [2.66-3.00]) for patients with new onset AF after controlling for all other potential risk factors.

conclusionsNew onset AF in trauma patients was associated with increased incidence of myocardial infarction (MI), cerebral vascular accident (CVA), and mortality during index hospitalization in this study.

Indexed as

Atrial FibrillationAdultAgedAged, 80 and overFemaleFloridaHumansMaleMedicareMiddle AgedMyocardial InfarctionRisk FactorsStrokeUnited Statesatrial fibrillationcardiopulmonary medicine, cerebrovascular accidentemergency medicinehospitalizationmyocardial infarctionstroketrauma

Identifiers

PMID33691355
PMCPMC8159849
OpenAlexW3134361244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.