Evidence map›Paper›PMID 33691130›Full record

ArticleImmunity2021

A neu(ronal) player joins the T regulatory game.

Samantha B Larsen, Shruti Naik

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Samantha B LarsenNeuroscience Institute, New York University Langone Health, 550 First Avenue, New York, NY 10016, USA.
Shruti NaikDepartment of Pathology, Department of Medicine, Ronald O. Perelman Department of Dermatology, and Perlmutter Cancer Center, New York University Langone Health, 550 First Avenue, New York, NY 10016, USA. Electronic address: shruti.naik@nylangone.org.
NYU Langone Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The enteric nervous system is surfacing as a key regulator of intestinal immunity and a liaison of host-commensal interactions. In this issue, Yan et al. identify neuronal interleukin-6 as a potent modulator of regulatory T (Treg) cells in the intestine. This neuroimmune dialog is further refined by commensal microbiota, which impact the enteric nervous system and consequently the intestinal Treg cell pool.

Indexed as

Enteric Nervous SystemMicrobiotaIntestinesSymbiosisT-Lymphocytes, Regulatory

Identifiers

PMID33691130
OpenAlexW3134213852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.