Evidence map›Paper›PMID 33690713›Full record

Trial reportPloS one2021

Technical results from a trial of the FREO2 Low-Pressure Oxygen Storage system, Mbarara Regional Referral Hospital, Uganda.

David Peake, James Black, Elias Kumbakumba, Sheillah Bagayana, Celestine Barigye, Peter Moschovis, Ivan Muhumuza, Frank Kiwanuka, Patrick Semata, Kevin Rassool and 2 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

David PeakeFREO2 Foundation Australia Ltd, Melbourne, Australia.ORCID 0000-0003-4852-624X
James BlackFREO2 Foundation Australia Ltd, Melbourne, Australia.
Elias KumbakumbaMbarara Regional Referral Hospital, Mbarara, Uganda.
Sheillah BagayanaMbarara Regional Referral Hospital, Mbarara, Uganda.
Celestine BarigyeMbarara Regional Referral Hospital, Mbarara, Uganda.
Peter MoschovisMassachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America.
Ivan MuhumuzaMbarara Regional Referral Hospital, Mbarara, Uganda.
Frank KiwanukaMbarara Regional Referral Hospital, Mbarara, Uganda.
Patrick SemataMbarara Regional Referral Hospital, Mbarara, Uganda.
Kevin RassoolFREO2 Foundation Australia Ltd, Melbourne, Australia.
Bryn SobottFREO2 Foundation Australia Ltd, Melbourne, Australia.
Roger RassoolFREO2 Foundation Australia Ltd, Melbourne, Australia.
Mbarara National Referral Hospital · UGThe University of Melbourne · AUMbarara University of Science and Technology · UGHarvard University · US

Funding

The effect of household air pollution on lung function growth in infants with pneumonia in sub-Saharan Africa.K23ES030399 · NIEHS · MASSACHUSETTS GENERAL HOSPITAL · PI MOSCHOVIS, PETER P · 2019 to 2024
$1.1M
NIEHS NIH HHS K23 ES030399
6 · The paper itself

Abstract

Increased access to reliable medical oxygen would reduce the global burden of pneumonia. Oxygen concentrators have been shown to be an effective solution, however they have significant drawbacks when used in low-resource environments where pneumonia burden is the heaviest. Low quality grid power can damage oxygen concentrators and blackouts can prevent at-risk patients from receiving continual oxygen therapy. Gaps in prescribed oxygen flow can result in acquired brain injuries, extended hypoxemia and death. The FREO2 Low-Pressure Oxygen Storage (LPOS) system consists of a suite of improvements to a standard oxygen concentrator which address these limitations. This study reports the technical results of a field trial of the system in Mbarara, Uganda. During this trial, oxygen supplied from the LPOS system was distributed to four beds in the paediatric ward of Mbarara Regional Referral Hospital. Over a three-month period, medical-grade oxygen was made available to patients 100% of the time. This period was sufficient to quantify the ability of the LPOS system to deal with blackouts, maintenance, and an unscheduled repair to the LPOS store.

Indexed as

ChildEquipment DesignHospitalsHumansHypoxiaOxygenOxygen Inhalation TherapyPneumoniaReferral and ConsultationUgandaOxygen

Identifiers

PMID33690713
PMCPMC7942979
OpenAlexW3134350315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.