Evidence map›Paper›PMID 33690651›Full record

ArticlePloS one2021

Genome-wide analysis of nearly all the victims of a 6200 year old massacre.

Mario Novak, Iñigo Olalde, Harald Ringbauer, Nadin Rohland, James Ahern, Jacqueline Balen, Ivor Janković, Hrvoje Potrebica, Ron Pinhasi, David Reich

Abstract readHistorical Article
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  4. The persistence and loss of hard selective sweeps amid admixture in ancient Eurasians.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
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  7. Global patterns of natural selection inferred using ancient DNA.bioRxiv : the preprint server for biology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mario NovakCentre for Applied Bioanthropology, Institute for Anthropological Research, Zagreb, Croatia.ORCID 0000-0002-4567-8742
Iñigo OlaldeInstitute of Evolutionary Biology, CSIC - Universitat Pompeu Fabra, Barcelona, Spain.
Harald RingbauerDepartment of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Nadin RohlandDepartment of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
James AhernDepartment of Anthropology, University of Wyoming, Laramie, Wyoming, United States of America.
Jacqueline BalenArchaeological Museum in Zagreb, Zagreb, Croatia.
Ivor JankovićCentre for Applied Bioanthropology, Institute for Anthropological Research, Zagreb, Croatia.
Hrvoje PotrebicaFaculty of Humanities and Social Sciences, University of Zagreb, Zagreb, Croatia.
Ron PinhasiDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
David ReichDepartment of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.

Funding

Population mixture in evolutionary and medical geneticsR01GM100233 · NIGMS · HARVARD MEDICAL SCHOOL · PI PATTERSON, NICK J, REICH, DAVID E · 2012 to 2019
$2.7M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM100233
6 · The paper itself

Abstract

Paleogenomic and bioanthropological studies of ancient massacres have highlighted sites where the victims were male and plausibly died all in battle, or were executed members of the same family as might be expected from a killing intentionally directed at subsets of a community, or where the massacred individuals were plausibly members of a migrant community in conflict with previously established groups, or where there was evidence that the killing was part of a religious ritual. Here we provide evidence of killing on a massive scale in prehistory that was not directed to a specific family, based on genome-wide ancient DNA for 38 of the 41 documented victims of a 6,200 year old massacre in Potočani, Croatia and combining our results with bioanthropological data. We highlight three results: (i) the majority of individuals were unrelated and instead were a sample of what was clearly a large farming population, (ii) the ancestry of the individuals was homogenous which makes it unlikely that the massacre was linked to the arrival of new genetic ancestry, and (iii) there were approximately equal numbers of males and females. Combined with the bioanthropological evidence that the victims were of a wide range of ages, these results show that large-scale indiscriminate killing is a horror that is not just a feature of the modern and historic periods, but was also a significant process in pre-state societies.

Indexed as

CroatiaDisaster VictimsFemaleForensic AnthropologyHistory, AncientHumansMalePedigreeWhole Genome Sequencing

Identifiers

PMID33690651
PMCPMC7946188

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.