Evidence map›Paper›PMID 33690644›Full record

ArticlePloS one2021

Design features and elemental/metal analysis of the atomizers in pod-style electronic cigarettes.

Esther E Omaiye, Monique Williams, Krassimir N Bozhilov, Prue Talbot

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Esther E OmaiyeEnvironmental Toxicology Graduate Program, University of California Riverside, Riverside, CA, United States of America.
Monique WilliamsDepartment of Molecular, Cell and Systems Biology, University of California Riverside, Riverside, CA, United States of America.
Krassimir N BozhilovCentral Facility for Advanced Microscopy and Microanalysis, University of California Riverside, Riverside, CA, United States of America.
Prue TalbotDepartment of Molecular, Cell and Systems Biology, University of California Riverside, Riverside, CA, United States of America.ORCID 0000-0001-8833-0845

Funding

Research Training in Environmental ToxicologyT32ES018827 · NIEHS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Yinsheng Wang · 2010 to 2026
$5.3M
Metals in Electronic Cigarette Aerosol R01DA036493 · NIDA · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI TALBOT, PRUDENCE · 2014 to 2018
$3.6M
NIDA NIH HHS R01 DA036493NIEHS NIH HHS T32 ES018827
6 · The paper itself

Abstract

backgroundThe atomizers of electronic cigarettes (ECs) contain metals that transfer to the aerosol upon heating and may present health hazards. This study analyzed 4th-generation EC pod atomizer design features and characterized their elemental/metal composition.

methodsEleven EC pods from six brands/manufacturers were purchased at local shops and online. Pods were dissected and imaged using a Canon EOS Rebel SL2 camera. Elemental analysis and mapping of atomizer components was done using a scanning electron microscope coupled with an energy dispersive x-ray spectrometer.

resultsEC pods varied in size and design. The internal atomizer components were similar across brands except for variations occurring mainly in the wicks and filaments of some products. The filaments were either Elinvar (nickel, iron, and chromium) (36.4%), nichrome (36.4%), iron-chromium (18.2%), or nickel (9%). Thick wires present in 55% of the atomizers were mainly nickel and were joined to filaments by brazing. Wire-connector joints were Elinvar. Metal air tubes were made of Elinvar (50%), nickel, zinc, copper, and tin (37.5%), and nickel and copper (12.5%). Most of the wick components were silica, except for two pods (PHIX and Mico), which were mainly ceramic. Connectors contained gold-plated nickel, iron-chromium multiple alloys of nickel, zinc, gold, iron, and copper. Wick chambers were made of Elinvar. Outer casings were either nickel, copper-tin, or nickel-copper alloys. Magnets were nickel with minor iron, copper, and sulfur. Some frequently occurring elements were high in relative abundance in atomizer components.

conclusionsThe atomizers of pods are similar to previous generations, with the introduction of ceramic wicks and magnets in the newer generations. The elements in EC atomizers may transfer into aerosols and adversely affect health and accumulate in the environment.

Indexed as

Electronic Nicotine Delivery SystemsNebulizers and VaporizersAerosolsEquipment DesignHumansMetalsSpectrometry, X-Ray EmissionAerosolsMetals

Identifiers

PMID33690644
PMCPMC7943009

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.