ArticleNature2021
Detection of a SARS-CoV-2 variant of concern in South Africa.
Abstract read
In one paragraph
Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,054 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
1,054citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1,054 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global health preparedness for biosecurity threats: a review of emerging technologies and solutions.Frontiers in public health · 2026Pooled it
- Efficacy, immunogenicity, and safety of heterologous boosting with a novel chimera Chinese mRNA (RQ3013) SARS-CoV-2 vaccine: A randomized, double-blind, active-controlled trial.Human vaccines & immunotherapeutics · 2025Trial
- Comparative analysis of neutralization assays performed using live SARS-CoV-2 virus and pseudovirus to assess immunogenicity of a bivalent SARS-CoV-2 protein vaccine in humans.Frontiers in immunology · 2025Trial
- Broad cross-T cell immunity between emerging SARS-CoV-2 serotypes waved by spike-signature mutations.Emerging microbes & infections · 2026Article
- Nanobodies targeting SARS-CoV-2 variants.Acta pharmaceutica Sinica. B · 2026Review
- Inferring variant-specific effective reproduction numbers from combined case and sequencing data.eLife · 2026Article
- The strategic importance of mRNA vaccine technologies in Africa for achieving public health independence.Communications medicine · 2026Article
- Immunogenicity and protective efficacy on non-adjuvanted CD40-targeting SARS-CoV-2 vaccines in non-human primates.EBioMedicine · 2026Article
- Genomic surveillance of SARS-CoV-2: a resource-efficient wastewater-based workflow.Molecular biology reports · 2026Article
- SARS-CoV-2 saltational events are recurrent and trace to persistent human infections.bioRxiv : the preprint server for biology · 2026Article
- Development of a recombinant single-cycle influenza viral vector as an intranasal vaccine against SARS-CoV-2.Scientific reports · 2026Article
- Genomic Surveillance of SARS-CoV-2 in Senegal (2020-2024): Variant Turnover, Omicron Introductions, and Interregional Spread.Influenza and other respiratory viruses · 2026Article
- Article
- Multiplexed antigen panel analysis identifies B cell phenotype and receptor genetic contributions to antibody breadth.Immunity · 2026Article
- SARS-CoV-2 Variants and Immune Evasion: Mapping the Future of Vaccine Design.Reviews in medical virology · 2026Review
- Global approaches to infectious disease surveillance and modeling.Nature medicine · 2026Review
- Viral genotype and the pace of epidemic waves: an assessment from SARS-CoV 2 genomics and wastewater surveillance data.Archives of virology · 2026Article
- Two years of SARS-CoV-2 genomic surveillance capacity development in Guinea.Scientific reports · 2026Article
- Spectroscopic secondary structure fingerprint of β-variant of SARS-CoV-2 spike glycoprotein.European biophysics journal : EBJ · 2026Article
- Self-amplifying COVID-19 mRNA vaccination induces longitudinally enhanced antibody function in a Phase 3 trial.NPJ vaccines · 2026Article
994 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
47 authors.
Houriiyah Tegally *KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Eduan Wilkinson *KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Marta Giovanetti *Laboratorio de Flavivirus, Fundacao Oswaldo Cruz, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0002-5849-7326
Arash Iranzadeh *Computational Biology Division, Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa.
Vagner FonsecaKwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.ORCID http://orcid.org/0000-0001-5521-6448
Jennifer GiandhariKwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Deelan DoolabhDivision of Medical Virology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Sureshnee PillayKwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Emmanuel James SanKwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Nokukhanya MsomiDiscipline of Virology, School of Laboratory Medicine and Medical Sciences and National Health Laboratory Service (NHLS), University of KwaZulu-Natal, Durban, South Africa.
Koleka MlisanaNHLS, Johannesburg, South Africa.
Anne von GottbergNational Institute for Communicable Diseases, NHLS, Johannesburg, South Africa.
Sibongile WalazaNational Institute for Communicable Diseases, NHLS, Johannesburg, South Africa.
Mushal AllamNational Institute for Communicable Diseases, NHLS, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-9875-6716
Arshad IsmailNational Institute for Communicable Diseases, NHLS, Johannesburg, South Africa.ORCID http://orcid.org/0000-0003-4672-5915
Thabo MohaleNational Institute for Communicable Diseases, NHLS, Johannesburg, South Africa.
Allison J GlassSchool of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Susan EngelbrechtDivision of Medical Virology, Faculty of Medicine and Health Sciences, Stellenbosch University and NHLS Tygerberg Hospital, Cape Town, South Africa.ORCID http://orcid.org/0000-0002-1318-5994
Gert Van ZylDivision of Medical Virology, Faculty of Medicine and Health Sciences, Stellenbosch University and NHLS Tygerberg Hospital, Cape Town, South Africa.ORCID http://orcid.org/0000-0003-3021-5101
Wolfgang PreiserDivision of Medical Virology, Faculty of Medicine and Health Sciences, Stellenbosch University and NHLS Tygerberg Hospital, Cape Town, South Africa.ORCID http://orcid.org/0000-0002-0254-7910
Francesco PetruccioneCentre for Quantum Technology, University of KwaZulu-Natal, Durban, South Africa.
Alex SigalAfrica Health Research Institute, Durban, South Africa.
Diana HardieDivision of Medical Virology, NHLS Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.
Gert MaraisDivision of Medical Virology, NHLS Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.
Nei-Yuan HsiaoDivision of Medical Virology, NHLS Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.
Stephen KorsmanDivision of Medical Virology, NHLS Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.
Mary-Ann DaviesCentre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa.
Lynn TyersDivision of Medical Virology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Innocent MudauDivision of Medical Virology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Denis YorkMolecular Diagnostics Services, Durban, South Africa.
Caroline MasloDepartment of Quality Leadership, Netcare Hospitals, Johannesburg, South Africa.
Dominique GoedhalsDivision of Virology, NHLS Universitas Academic Laboratories, University of The Free State, Bloemfontein, South Africa.
Shareef AbrahamsNHLS, Port Elizabeth, South Africa.
Oluwakemi Laguda-AkingbaNHLS, Port Elizabeth, South Africa.
Arghavan Alisoltani-DehkordiDivision of Medical Virology, Department of Pathology, University of Cape Town, Cape Town, South Africa.
Adam GodzikDivision of Biomedical Sciences, University of California Riverside School of Medicine, Riverside, CA, USA.
Constantinos Kurt WibmerNational Institute for Communicable Diseases, NHLS, Johannesburg, South Africa.
Bryan Trevor SewellStructural Biology Research Unit, Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa.
José LourençoDepartment of Zoology, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-9318-2581
Luiz Carlos Junior AlcantaraLaboratorio de Flavivirus, Fundacao Oswaldo Cruz, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0002-6769-9931
Sergei L Kosakovsky PondInstitute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA, USA.
Steven WeaverInstitute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA, USA.
Darren MartinComputational Biology Division, Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa.
Richard J LessellsKwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.ORCID http://orcid.org/0000-0003-0926-710X
Jinal N BhimanNational Institute for Communicable Diseases, NHLS, Johannesburg, South Africa.ORCID http://orcid.org/0000-0001-6354-4003
Carolyn WilliamsonDivision of Medical Virology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Tulio de OliveiraKwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa. tuliodna@gmail.com.ORCID http://orcid.org/0000-0002-3027-5254
Funding
No grant is acknowledged in the PubMed record.
Abstract
Continued uncontrolled transmission of SARS-CoV-2 in many parts of the world is creating conditions for substantial evolutionary changes to the virus
Indexed as
MutationPhylogenyPhylogeographyCOVID-19DNA Mutational AnalysisEvolution, MolecularGenetic FitnessHumansImmune EvasionModels, MolecularSARS-CoV-2Selection, GeneticSouth AfricaSpike Glycoprotein, CoronavirusTime FactorsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2
Identifiers
PMID
33690265What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.