ArticleAmerican journal of respiratory and critical care medicine2021
Blood Transcriptomics Predicts Progression of Pulmonary Fibrosis and Associated Natural Killer Cells.
Open access · greenAbstract readComparative Study
In one paragraph
Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Blood gene expression risk profiles and interstitial lung abnormalities: COPDGene and ECLIPSE cohort studies.Respiratory research · 2022Pooled it
- Trial
- The transcriptome of CD14The European respiratory journal · 2026Article
- Expression of complement pathway genes is associated with progression of idiopathic pulmonary fibrosis.Respiratory research · 2026Article
- Hesperetin Alleviates Bleomycin-Induced Pulmonary Fibrosis by Modulating Cellular Senescence and Promoting Impaired Autophagy in a CISD2-Dependent Manner.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Review
- LungGENIE: the lung gene-expression and network imputation engine.BMC genomics · 2025Article
- Article
- Transcriptome-Wide Association Study of Idiopathic Pulmonary Fibrosis Survival IdentifiesAmerican journal of respiratory and critical care medicine · 2024Article
- RIOK2 transcriptionally regulates TRiC and dyskerin complexes to prevent telomere shortening.Nature communications · 2024Article
- The Role of Inflammation and Fibrosis in Interstitial Lung Disease Treatment Decisions.American journal of respiratory and critical care medicine · 2024Article
- Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine.American journal of respiratory and critical care medicine · 2024Review
- Article
- Diagnostic potential of genomic blood biomarkers of pulmonary fibrosis in a prospective cohort.PloS one · 2024Article
- Approach to Clinical Trials for the Prevention of Pulmonary Fibrosis.Annals of the American Thoracic Society · 2023Article
- To Progress or Not to Progress, That Is the Question! Progression in Fibrotic Interstitial Lung Disease.American journal of respiratory and critical care medicine · 2023Article
- PCSK6 and Survival in Idiopathic Pulmonary Fibrosis.American journal of respiratory and critical care medicine · 2023Article
- IL-8 concurrently promotes idiopathic pulmonary fibrosis mesenchymal progenitor cell senescence and PD-L1 expression enabling escape from immune cell surveillance.American journal of physiology. Lung cellular and molecular physiology · 2023Article
- Integrative multi-omics analysis reveals novel idiopathic pulmonary fibrosis endotypes associated with disease progression.Respiratory research · 2023Article
- The Effects of Interstitial Lung Diseases on Alveolar Extracellular Vesicles Profile: A Multicenter Study.International journal of molecular sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 11 institutions in 2 countries.
Yong HuangDivision of Pulmonary and Critical Care Medicine, The University of Virginia, Charlottesville, Virginia.
Justin M OldhamDivision of Pulmonary, Critical Care, and Sleep Medicine, The University of California at Davis, Sacramento, California.ORCID 0000-0003-4957-8869
Shwu-Fan MaDivision of Pulmonary and Critical Care Medicine, The University of Virginia, Charlottesville, Virginia.ORCID 0000-0002-3058-9480
Avraham UntermanSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale School of Medicine, Yale University, New Haven, Connecticut.
Shu-Yi LiaoDepartment of Medicine, National Jewish Health, Denver, Colorado.
Andrew J BarrosDivision of Pulmonary and Critical Care Medicine, The University of Virginia, Charlottesville, Virginia.
Catherine A BonhamDivision of Pulmonary and Critical Care Medicine, The University of Virginia, Charlottesville, Virginia.
John S KimDivision of Pulmonary and Critical Care Medicine, The University of Virginia, Charlottesville, Virginia.
Rekha VijSection of Pulmonary and Critical Care Medicine and.
Ayodeji AdegunsoyeSection of Pulmonary and Critical Care Medicine and.
Mary E StrekSection of Pulmonary and Critical Care Medicine and.
Philip L MolyneauxNational Heart and Lung Institute, Imperial College, London, United Kingdom.
Toby M MaherNational Heart and Lung Institute, Imperial College, London, United Kingdom.ORCID 0000-0001-7192-9149
Jose D Herazo-MayaDivision of Pulmonary, Critical Care, and Sleep Medicine, Tampa General Hospital, University of South Florida, Tampa, Florida.
Naftali KaminskiSection of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale School of Medicine, Yale University, New Haven, Connecticut.ORCID 0000-0001-5917-4601
Bethany B MooreDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan; and.
Fernando J MartinezInternal Medicine, Weill Cornell Medical College, Cornell University, New York, New York.
Imre NothDivision of Pulmonary and Critical Care Medicine, The University of Virginia, Charlottesville, Virginia.
University of Virginia · USPulmonary and Critical Care Associates · USYale University · USCornell University · USNational Jewish Health · USRoyal Brompton Hospital · GBUniversity of California System · USUniversity of Chicago · USUniversity of Michigan · USUniversity of Southern California · USUniversity of South Florida · US
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M1/2 Prospective tReatment EffiCacy in IPF uSlng genOtype for Nac Selection (PRECISIONS) trial and Molecular Endophenotyping in Idiopathic Pulmonary Fibrosis and Interstitial Lung Diseases studyUH3HL145266 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MARTINEZ, FERNANDO J, NOTH, IMRE · 2021 to 2025
$11.6MImmunobiology of Lung Injury and FibrosisR35HL144481 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOORE, BETHANY B. · 2019 to 2024
$5.2MArchitectural structure and regulation of TOLLIP in IPFR01HL130796 · NHLBI · UNIVERSITY OF VIRGINIA · PI NOTH, IMRE · 2016 to 2019
$3.1M1/2 Prospective tReatment EffiCacy in IPF uSlng genOtype for Nac Selection (PRECISIONS) trial and Molecular Endophenotyping in Idiopathic Pulmonary Fibrosis and Interstitial Lung Diseases studyUG3HL145266 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MARTINEZ, FERNANDO J, NOTH, IMRE · 2019 to 2019
$977kElucidating the Genomic Determinants of Outcomes in Idiopathic Pulmonary FibrosisK23HL138190 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OLDHAM, JUSTIN M · 2017 to 2021
$914kImproving Pulmonary Fibrosis Classification with Genomics Informed Phenotypic ClustersK23HL146942 · NHLBI · UNIVERSITY OF CHICAGO · PI ADEGUNSOYE, AYODEJI · 2020 to 2024
$810kT cells in idiopathic pulmonary fibrosisK23HL143135 · NHLBI · UNIVERSITY OF VIRGINIA · PI BONHAM, CATHERINE ANN · 2018 to 2021
$662kNCATS NIH HHS UL1 TR001863NHLBI NIH HHS K23 HL138190NHLBI NIH HHS K23 HL143135NHLBI NIH HHS K23 HL146942NHLBI NIH HHS L30 HL134087NHLBI NIH HHS R01 HL130796NHLBI NIH HHS R35 HL144481NHLBI NIH HHS UG3 HL145266NHLBI NIH HHS UH3 HL145266
Abstract
PubMed holds no abstract for this paper.
Indexed as
Disease ProgressionKiller Cells, NaturalPredictive Value of TestsTranscriptomeAgedBiomarkersCohort StudiesCross-Sectional StudiesFemaleHumansIdiopathic Pulmonary FibrosisLongitudinal StudiesMaleMiddle AgedBiomarkerscell type composition deconvolutionidiopathic pulmonary fibrosislongitudinal changes of blood gene expressionmultigene predictor for progressionrelative decline of FVC
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.