Evidence map›Paper›PMID 33689532›Full record

ArticleCurrent eye research2021

Progressive Loss of Retinal Ganglion Cells in Activating Protein-2β Neural Crest Cell Knockout Mice.

Aftab Taiyab, Anthony Saraco, Monica Akula, Paula Deschamps, Alexander K Ball, Trevor Williams, Judith A West-Mays

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current eye research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Studies of mice with a large deletion of the ARPKD-associatedbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Aftab TaiyabHealth Sciences Centre, McMaster University, Hamilton, Ontario, Canada.
Anthony SaracoHealth Sciences Centre, McMaster University, Hamilton, Ontario, Canada.
Monica AkulaHealth Sciences Centre, McMaster University, Hamilton, Ontario, Canada.
Paula DeschampsHealth Sciences Centre, McMaster University, Hamilton, Ontario, Canada.
Alexander K BallHealth Sciences Centre, McMaster University, Hamilton, Ontario, Canada.
Trevor WilliamsCraniofacial Biology, University of Colorado, Aurora, Colorado, USA.
Judith A West-MaysHealth Sciences Centre, McMaster University, Hamilton, Ontario, Canada.
McMaster University Medical Centre · CAHealth Sciences Centre · CAUniversity of Colorado Denver · US

Funding

Role of AP-2beta in Anterior Segment DevelopmentR01EY025789 · NEI · MCMASTER UNIVERSITY · PI WEST-MAYS, JUDITH A, WILLIAMS, TREVOR J · 2015 to 2023
$2.8M
NEI NIH HHS R01 EY025789
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsDisease ProgressionElectrophoresisGlaucomaGlial Fibrillary Acidic ProteinImmunohistochemistryIntraocular PressureMiceMice, KnockoutMicrogliaNeural CrestPolymerase Chain ReactionRetinal DiseasesRetinal Ganglion CellsTonometry, OcularTranscription Factor AP-2Glial Fibrillary Acidic Proteinglial fibrillary astrocytic protein, mousePou4f1 protein, mouseTfap2b protein, mouseTranscription Factor AP-2Transcription Factor Brn-3AVimentinVim protein, mousedevelopmentintraocular pressureknockout mousemacrogliaMüller cellsNeural crestretinal ganglion cells

Identifiers

PMID33689532
PMCPMC8419028
OpenAlexW3133934032

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.