Evidence map›Paper›PMID 33689138›Full record

ArticleAnnals of nuclear medicine2021

Guang Ma, Cheng Liu, Weiling Lian, Yongping Zhang, Huiyu Yuan, Yingjian Zhang, Shaoli Song, Zhongyi Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of nuclear medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Evaluating [International journal of molecular sciences · 2023
    Article
  4. Article
  5. 3'-[Journal of translational medicine · 2022
    Article
  6. Novel applications of molecular imaging to guide breast cancer therapy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Guang Ma *Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, No.270, Dong'an Road, Xuhui District, Shanghai, 200032, China.
Cheng Liu *Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, No.270, Dong'an Road, Xuhui District, Shanghai, 200032, China.
Weiling Lian *Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, No.270, Dong'an Road, Xuhui District, Shanghai, 200032, China.
Yongping ZhangDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No.270, Dong'an Road, Xuhui District, Shanghai, 200032, China.
Huiyu YuanDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No.270, Dong'an Road, Xuhui District, Shanghai, 200032, China.
Yingjian ZhangDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No.270, Dong'an Road, Xuhui District, Shanghai, 200032, China.
Shaoli SongDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No.270, Dong'an Road, Xuhui District, Shanghai, 200032, China. shaoli-song@163.com.
Zhongyi YangDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No.270, Dong'an Road, Xuhui District, Shanghai, 200032, China. yangzhongyi21@163.com.ORCID http://orcid.org/0000-0001-6195-9942
Shanghai Medical College of Fudan University · CN

Funding

Shanghai Committee of Science and Technology Fund 19ZR1411300Shanghai Engineering Research Center of Molecular Imaging Probes Program 19DZ2282200Shanghai Municipal Health Commission 202040267Shanghai Sailing Program 20YF1408500the Science and Technology Development Fund of Shanghai Pudong New Area PKJ2020-Y54
6 · The paper itself

Abstract

purposeOur study was to investigate

methodsMDA-MB-231 and MDA-MB-468 cell lines and corresponding subcutaneous tumor models in CB17-SCID mice were used. Cell viability assay, cell-cycle analysis, and western blotting were performed in vitro experiments.

resultsIn the presence of Palbociclib (CDK4/6 inhibitor), the results of in vitro experiments showed that protein pRB and E2F levels were significantly down-regulated in MDA-MB-231 cells leading to G0/G1 arrest with consumption in S phase compared with MDA-MB-468 cells. In PET/CT imaging, the

conclusion

Indexed as

Cyclin-Dependent Kinase 4Cyclin-Dependent Kinase 6DideoxynucleosidesPositron Emission Tomography Computed TomographyProtein Kinase InhibitorsTriple Negative Breast NeoplasmsAnimalsCell Line, TumorFemaleHumansMicePiperazinesPyridinesTreatment OutcomealovudineCyclin-Dependent Kinase 4Cyclin-Dependent Kinase 6DideoxynucleosidespalbociclibPiperazinesProtein Kinase InhibitorsPyridines18F-FLTCDK4/6 inhibitorEarly treatment responseMonitorTriple negative breast cancer

Identifiers

PMID33689138
OpenAlexW3134716831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.