SynthesisArchives of sexual behavior2021
Mediators of the Disparities in Depression Between Sexual Minority and Heterosexual Individuals: A Systematic Review.
Synthesis in Archives of sexual behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- How much is sexual minority stress confounded with familial causes? A systematic multilevel meta-analysis.Psychological medicine · 2026Pooled it
- Prevalence, severity and risk factors for mental disorders among sexual and gender minority young people: a systematic review of systematic reviews and meta-analyses.European child & adolescent psychiatry · 2025Pooled it
- Prevalence, severity and risk factors of psychiatric disorders amongst sexual and gender diverse young people during the COVID-19 pandemic: A systematic review.Clinical child psychology and psychiatry · 2024Pooled it
- Pooled it
- Parental Beliefs in Relation to Sexual Minority Young Adults' Critical Consciousness, Mental Health, and Substance Use.Substance use & misuse · 2026Article
- Article
- Comparison of depressive symptoms between heterosexual and sexual minority university students: network analysis.Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS · 2026Article
- Intimate Partner Violence and its Association with Symptoms of Depression and Post-Traumatic Stress Disorder Among HIV-Negative Cisgender Sexual Minority Men in the United States.Sexual and gender diversity in social services · 2026Article
- LGBTQ+ experiences of accessing NHS adult mental health services during COVID-19 in an area of North West England: a qualitative interview study.BMC health services research · 2026Article
- Hispanic sexual minority individuals, linguistic acculturation, and behavioral health: Evidence of a healthy migrant effect.Social psychiatry and psychiatric epidemiology · 2026Article
- Sexual Orientation, Pubertal Timing, Inhibitory Control, and Adolescent Depressive Symptoms: A Birth Cohort Study.Archives of sexual behavior · 2025Article
- Loneliness and Intersectional Discrimination Among Aging LGBT People in Spain: A Qualitative Research Study of Gay Men.Behavioral sciences (Basel, Switzerland) · 2025Article
- Resilience Through Social Support: An Intersectional Analysis of Sexual Minority Women's Social Resources for Wellbeing.Journal of homosexuality · 2025Article
- Experiences and Minority Stress of Sexual Minority Student Athletes in Chinese Collegiate Sports.Archives of sexual behavior · 2025Article
- Rural-urban Residence, Minority Stress, and Tobacco Use among Sexual and Gender Minority Young Adults in Oklahoma and Surrounding States.Journal of health care for the poor and underserved · 2025Article
- Examining Gender Differences in Aggression as a Predictor of Anxiety, Depression, and Suicide in a Cross-Sectional French Sample.Health science reports · 2025Article
- The role of victimisation and sleep quality in self-harm and depression among sexual minority adolescents. A prospective cohort study.European child & adolescent psychiatry · 2024Article
- The Chain Mediation Effect of Victimization and Neuroticism on the Association Between Sexual Orientation and Depressive Symptoms: A Prospective Birth Cohort Study.Archives of sexual behavior · 2024Article
- The Intersection of Sexual Orientation, Substance Use, and Mental Health: Findings from Hints 5.Healthcare (Basel, Switzerland) · 2024Article
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evidence suggests that sexual minorities (e.g., those identifying as lesbian, gay, or bisexual) experience increased rates of depression compared to heterosexual individuals. Minority stress theory suggests that this disparity is due to stigma experienced by sexual minorities. Stigma processes are proposed to contribute to reduced coping/support resources and increased vulnerability processes for mental health problems. This review provided a systematic examination of research assessing the evidence for mediating factors that help explain such disparities. A literature search was conducted using the databases PubMed, PsycINFO, and Web of Science. The review included 40 identified studies that examined mediators of sexual minority status and depressive outcomes using a between-group design (i.e., heterosexual versus sexual minority participants). Studies of adolescents and adult samples were both included. The most common findings were consistent with the suggestion that stressors such as victimization, harassment, abuse, and increased stress, as well as lower social and family support, may contribute to differing depression rates in sexual minority compared to heterosexual individuals. Differences in psychological processes such as self-esteem and rumination may also play a role but have had insufficient research attention so far. However, caution is needed because many papers had important methodological shortcomings such as the use of cross-sectional designs, inferior statistical analyses for mediation, or measures that had not been properly validated. Although firm conclusions cannot be drawn, the current evidence base highlights many factors potentially suitable for further exploration in high-quality longitudinal research or randomized studies intervening with the potential mediators.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.