SynthesisBJS open2021
Routine versus selective intraoperative cholangiography during cholecystectomy: systematic review, meta-analysis and health economic model analysis of iatrogenic bile duct injury.
Synthesis in BJS open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Risk factors and mitigating measures associated with bile duct injury during cholecystectomy: meta-analysis.BJS open · 2025Pooled it
- Benefits and risks of using laparoscopic ultrasonography versus intraoperative cholangiography during laparoscopic cholecystectomy for gallstone disease: a systematic review and meta-analysis.Surgical endoscopy · 2024Pooled it
- Selective intraoperative cholangiography should be considered over routine intraoperative cholangiography during cholecystectomy: a systematic review and meta-analysis.Surgical endoscopy · 2022Pooled it
- Intraoperative Cholangiography in Laparoscopic Cholecystectomy: A Systematic Review and Meta-Analysis.JSLS : Journal of the Society of Laparoendoscopic SurgeonsPooled it
- Article
- Prevention of bile duct injury - A bird's eye view.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Review
- Selective intraoperative cholangiography: A retrospective single-centre analysis compared with national data and implications for surgical training.Langenbeck's archives of surgery · 2026Article
- Navigating the Impossible Gallbladder: Bailout Strategies and Culture of Safety in Laparoscopic Cholecystectomy.Cureus · 2026Review
- Project interpret cholangiogram at the SAGES 2024 Education & Innovation Center: skill deficiency in bile duct injury recognition among surgical residents.Surgical endoscopy · 2025Article
- A preliminary study using luminol-enhanced intraoperative bile duct imaging technique in rabbits.Scientific reports · 2025Article
- Robotic versus laparoscopic cholecystectomy for difficult gallbladders: an observational study of tertiary centre cases.Surgical endoscopy · 2025Observational
- The difficult laparoscopic cholecystectomy: a narrative review.BMC surgery · 2025Review
- Selective vs Routine Cholangiography Across a Health Care Enterprise.JAMA surgery · 2025Article
- Four-Year Report of Iatrogenic Bile Duct Injury Repair from a Referral Hepatobiliary Center.Middle East journal of digestive diseases · 2024Article
- Is there a role for routine intraoperative cholangiogram in diagnosing CBD stones in patients with normal liver function tests? A prospective study.Innovative surgical sciences · 2024Article
- An uncommon case of right hepatic duct entering cystic duct associated to multiple complications of biliary tract disease: acute pancreatitis, hepatolithiasis, acute cholecystitis and hepatic abscess.Journal of surgical case reports · 2024Article
- Review
- Bile duct injuries during laparoscopic cholecystectomies: an 11-year population-based study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Article
- Length of the Remnant Cystic Duct and Bile Duct Stone Recurrence: a Case‒Control Study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- Systematic intraoperative cholangiography during elective laparoscopic cholecystectomy: Is it a justifiable practice?Annals of hepato-biliary-pancreatic surgery · 2023Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBile duct injury (BDI) is a severe complication following cholecystectomy. Early recognition and treatment of BDI has been shown to reduce costs and improve patients' quality of life. The aim of this study was to assess the effect and cost-effectiveness of routine versus selective intraoperative cholangiography (IOC) in cholecystectomy.
methodsA systematic review and meta-analysis, combined with a health economic model analysis in the Swedish setting, was performed. Costs per quality-adjusted life-year (QALY) for routine versus selective IOC during cholecystectomy for different scenarios were calculated.
resultsIn this meta-analysis, eight studies with more than 2 million patients subjected to cholecystectomy and 9000 BDIs were included. The rate of BDI was estimated to 0.36 per cent when IOC was performed routinely, compared with to 0.53 per cent when used selectively, indicating an increased risk for BDI of 43 per cent when IOC was used selectively (odds ratio 1.43, 95 per cent c.i. 1.22 to 1.67). The model analysis estimated that seven injuries were avoided annually by routine IOC in Sweden, a population of 10 million. Over a 10-year period, 33 QALYs would be gained at an approximate net cost of €808 000 , at a cost per QALY of about €24 900.
conclusionRoutine IOC during cholecystectomy reduces the risk of BDI compared with the selective strategy and is a potentially cost-effective intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.