Evidence map›Paper›PMID 33688828›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2021

Home sleep apnea testing of adults with chronic heart failure.

Shengnan Li, Liyue Xu, Xiaosong Dong, Xueli Zhang, Brendan T Keenan, Fang Han, Taoran Bi, Yuan Chang, Yongbo Yu, Bing Zhou and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Chinese Guidelines for the Diagnosis and Surgical Treatment of Adult Obstructive Sleep Apnea (2024).World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
  5. Review
  6. Article
  7. Home monitoring for clinically suspected obstructive sleep apnea in pregnancy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  8. Article
  9. Diagnosis of Obstructive Sleep Apnea in Patients with Associated Comorbidity.Advances in experimental medicine and biology · 2022
    Review
  10. Article
  11. Home sleep apnea testing for chronic heart failure: time to break the Cheyne?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Shengnan LiDepartment of Respiratory Medicine, Peking University People's Hospital, Beijing, China.
Liyue XuDepartment of Respiratory Medicine, Peking University People's Hospital, Beijing, China.
Xiaosong DongDepartment of Respiratory Medicine, Peking University People's Hospital, Beijing, China.
Xueli ZhangDepartment of Respiratory Medicine, Peking University People's Hospital, Beijing, China.
Brendan T KeenanDepartment of Medicine and Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Fang HanDepartment of Respiratory Medicine, Peking University People's Hospital, Beijing, China.
Taoran BiDepartment of Respiratory Medicine, Peking University People's Hospital, Beijing, China.
Yuan ChangDepartment of Respiratory Medicine, Peking University International Hospital, Beijing, China.
Yongbo YuPKU-UPenn Sleep Center, Peking University International Hospital, Beijing, China.
Bing ZhouDepartment of Respiratory Medicine, Peking University People's Hospital, Beijing, China.
Allan I PackDepartment of Medicine and Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Samuel T KunaDepartment of Medicine and Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Peking University · CNPeking University People's Hospital · CNPeking University International Hospital · CNUniversity of Pennsylvania · USPhiladelphia VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesTo evaluate home sleep apnea testing (HSAT) using a type 3 portable monitor to help diagnose sleep-disordered breathing (SDB) and identify respiratory events including obstructive sleep apnea, central sleep apnea, and Cheyne-Stokes respiration in adults with stable chronic heart failure.

methodsEighty-four adults with chronic heart failure (86.9% males, age [mean ± standard deviation] 58.7 ± 16.3 years, body mass index 29.4 ± 13.0 kg/m², left ventricular ejection fraction 40.3% ± 11.5%) performed unattended HSAT followed by an in-laboratory polysomnography (PSG) with simultaneous portable monitor recording.

resultsThe apnea-hypopnea index was 22.0 ± 17.0 events/h according to HSAT, 26.8 ± 20.5 events/h on an in-laboratory portable monitor, and 23.8 ± 21.3 events/h using PSG (P = .373). A Bland-Altman analysis of the apnea-hypopnea index using HSAT vs PSG showed a mean difference (95% confidence interval) of -2.4 (-4.9 to 0.1) events/h and limits of agreement (±2 standard deviations) of -24.1 to 19.2 events/h. HSAT underestimated the apnea-hypopnea index to a greater extent at a higher apnea-hypopnea index (rho = -.358; P < .001). Similar levels of agreement from HSAT vs PSG were observed when comparing the obstructive apnea index, central apnea index, and percentage of time in a Cheyne-Stokes respiration pattern. When we used an apnea-hypopnea index ≥ 5 events/h to diagnose SDB, HSAT had 86.7% sensitivity, 76.5% specificity, 92.9% positive predictive value, and 61.9% negative predictive value compared to PSG. Detection of Cheyne-Stokes respiration using HSAT showed 94.6% sensitivity, 91.1% specificity, 88.6% positive predictive value, and 97.6% negative predictive value compared to PSG.

conclusionsHSAT with a type 3 portable monitor can help diagnose SDB and identify obstructive sleep apnea, central sleep apnea, and Cheyne-Stokes respiration events in adults with chronic heart failure.

Indexed as

Heart FailureSleep Apnea SyndromesAdultAgedFemaleHumansMaleMiddle AgedPolysomnographyStroke VolumeVentricular Function, Leftapnea-hypopnea indexchronic heart failurehome sleep apnea testingpolysomnogram

Identifiers

PMID33688828
PMCPMC8314621
OpenAlexW3134812715

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.