Evidence map›Paper›PMID 33688490›Full record

ArticleCanadian journal of gastroenterology & hepatology2021

Association between Gastroesophageal Reflux Disease and Elastographic Parameters of Liver Steatosis and Fibrosis: Controlled Attenuation Parameter and Liver Stiffness Measurements.

Ivana Mikolasevic, Goran Poropat, Tajana Filipec Kanizaj, Nadija Skenderevic, Marko Zelic, Marija Matasin, Luka Vranic, Andrea Kresovic, Goran Hauser

Abstract read
In one paragraph

Article in Canadian journal of gastroenterology & hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ivana MikolasevicDepartment of Gastroenterology, Clinical Hospital Center Rijeka, Rijeka, Croatia.ORCID 0000-0001-9676-0642
Goran PoropatDepartment of Gastroenterology, Clinical Hospital Center Rijeka, Rijeka, Croatia.ORCID 0000-0002-2007-9452
Tajana Filipec KanizajDepartment of Gastroenterology, University Hospital Merkur, Zagreb, Croatia.ORCID 0000-0002-9828-8916
Nadija SkenderevicDepartment of Gastroenterology, University Hospital Merkur, Zagreb, Croatia.ORCID 0000-0003-4296-6375
Marko ZelicFaculty of Medicine, Rijeka, Croatia.ORCID 0000-0001-8769-3089
Marija MatasinFaculty of Medicine, Zagreb, Croatia.ORCID 0000-0002-3953-8284
Luka VranicDepartment of Gastroenterology, Clinical Hospital Center Rijeka, Rijeka, Croatia.ORCID 0000-0003-2886-2668
Andrea KresovicDepartment of Gastroenterology, Clinical Hospital Center Rijeka, Rijeka, Croatia.ORCID 0000-0001-7570-3139
Goran HauserDepartment of Gastroenterology, Clinical Hospital Center Rijeka, Rijeka, Croatia.ORCID 0000-0002-4758-1717

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Our aim was to investigate the association among elastographic parameters of liver steatosis and fibrosis, controlled attenuation parameter (CAP) and liver stiffness measurement (LSM), with gastroesophageal reflux disease (GERD). Methods: In this prospective, cross-sectional study, we have evaluated 937 patients with one or more components of the metabolic syndrome who had an esophagogastroduodenoscopy (EGD) due to GERD symptoms. In all patients, a laboratory analysis, an abdominal ultrasound, and FibroScan measurements were done. GERD was defined by EGD. Results: The mean body mass index (BMI) of the study population was 30.95 ± 5.45 kg/m Conclusion: To the best of our knowledge, our study is the first to reveal a positive association between CAP as a surrogate marker of liver steatosis and GERD after adjustments for other clinical variables.

Indexed as

Elasticity Imaging TechniquesGastroesophageal RefluxNon-alcoholic Fatty Liver DiseaseCross-Sectional StudiesHumansLiverLiver CirrhosisProspective Studies

Identifiers

PMID33688490
PMCPMC7925017

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.