Evidence map›Paper›PMID 33688074›Full record

ArticleDevelopment (Cambridge, England)2021

Electrostatic plasma membrane targeting contributes to Dlg function in cell polarity and tumorigenesis.

Juan Lu, Wei Dong, Yan Tao, Yang Hong

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Electrical Forces in Lumen Formation.Reviews of physiology, biochemistry and pharmacology · 2025
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Evidence for a nuclear role forMolecular biology of the cell · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Juan LuDepartment of Cell Biology, University of Pittsburgh Medical School, Pittsburgh, PA 15261, USA.ORCID 0000-0001-5635-3233
Wei DongDepartment of Cell Biology, University of Pittsburgh Medical School, Pittsburgh, PA 15261, USA.ORCID 0000-0001-5519-4859
Yan TaoJiangsu University, Zhengjiang, Jiangsu 212013, People's Republic of China.
Yang HongDepartment of Cell Biology, University of Pittsburgh Medical School, Pittsburgh, PA 15261, USA yhong@pitt.edu.ORCID 0000-0003-2252-0798
University of Pittsburgh · USJiangsu University · CN

Funding

Plasma Membrane Targeting and Retargeting of Polarity ProteinsR01GM121534 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HONG, YANG · 2017 to 2025
$2.5M
Regulation of Adherens Junction Trafficking by Polarity ProteinsR01GM086423 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HONG, YANG · 2010 to 2014
$1.4M
Genomic Engineering in DrosophilaR21RR024869 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HONG, YANG · 2009 to 2010
$394k
Request for a Nikon A1 confocal microscopeS10OD019973 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WATKINS, SIMON C · 2015 to 2015
$358k
NCRR NIH HHS R21 RR024869NIGMS NIH HHS R01 GM086423NIGMS NIH HHS R01 GM121534NIH HHS S10 OD019973
6 · The paper itself

Abstract

Discs large (Dlg) is an essential polarity protein and a tumor suppressor originally characterized in

Indexed as

Static ElectricityAnimalsAnimals, Genetically ModifiedCarcinogenesisCell MembraneCell Physiological PhenomenaCell PolarityDrosophilaDrosophila ProteinsEpithelial CellsFemaleGenes, Tumor SuppressorMaleTumor Suppressor Proteinsdlg1 protein, DrosophilaDrosophila ProteinsTumor Suppressor ProteinsaPKCCell polarityDlgDrosophilaLglPar-6PhosphoinositidesPI(45)P2PI4PPolybasic domainScribTumorigenesis

Identifiers

PMID33688074
PMCPMC8034875
OpenAlexW3135014624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.