Evidence map›Paper›PMID 33688011›Full record

ArticlemBio2021

Understanding the Basis of METH Mouth Using a Rodent Model of Methamphetamine Injection, Sugar Consumption, and Streptococcus mutans Infection.

Hiu Ham Lee, Preethi Sudhakara, Shreena Desai, Kildare Miranda, Luis R Martinez

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Hiu Ham LeeDepartment of Biomedical Sciences, NYIT College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, New York, USA.
Preethi SudhakaraDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.
Shreena DesaiDepartment of Biomedical Sciences, NYIT College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, New York, USA.
Kildare MirandaInstituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Luis R MartinezDepartment of Biomedical Sciences, NYIT College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, New York, USA LMartinez@dental.ufl.edu.ORCID 0000-0001-6372-6501
New York Institute of Technology · USThe University of Texas at El Paso · USUniversidade Federal do Rio de Janeiro · BRUniversity of Florida · USUniversity of Miami · US

Funding

Unraveling Cryptococcus neoformans mechanisms of brain invasion and colonizationR01AI145559 · NIAID · UNIVERSITY OF TEXAS EL PASO · PI MARTINEZ, LUIS R · 2019 to 2023
$2.6M
NIAID NIH HHS R01 AI145559
6 · The paper itself

Abstract

"METH mouth" is a common consequence of chronic methamphetamine (METH) use, resulting in tooth decay and painful oral tissue inflammation that can progress to complete tooth loss. METH reduces the amount of saliva in the mouth, promoting bacterial growth, tooth decay, and oral tissue damage. This oral condition is worsened by METH users' compulsive behavior, including high rates of consumption of sugary drinks, recurrent tooth grinding, and a lack of frequent oral hygiene.

Indexed as

AnimalsBacterial AdhesionBiofilmsDental CariesDietary SugarsDisease Models, AnimalFemaleGram-Positive Bacterial InfectionsMaleMethamphetamineMiceMice, Inbred C57BLMouthStreptococcus mutansToothDietary SugarsMethamphetaminebiofilmschlorhexidinemethamphetamineMETH mouthStreptococcus mutanssucrose

Identifiers

PMID33688011
PMCPMC8092307
OpenAlexW3135669331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.