Evidence map›Paper›PMID 33688009›Full record

ArticlemBio2021

Insulinase-like Protease 1 Contributes to Macrogamont Formation in Cryptosporidium parvum.

Rui Xu, Yaoyu Feng, Lihua Xiao, L David Sibley

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Review
  6. Virulence · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Rui XuDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Yaoyu FengSchool of Resources and Environmental Engineering, East China University of Science and Technology, Shanghai, China.ORCID 0000-0002-8380-1246
Lihua XiaoCenter for Emerging and Zoonotic Diseases, College of Veterinary Medicine, South China Agriculture University, Guangzhou, China.
L David SibleyDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA sibley@wustl.edu.ORCID 0000-0001-7110-0285
South China Agricultural University · CNEast China University of Science and Technology · CNWashington University in St. Louis · US

Funding

Effect of Microbial Metabolites on Growth of CryptosporidiumR01AI145496 · NIAID · WASHINGTON UNIVERSITY · PI SIBLEY, L. DAVID · 2020 to 2023
$2.7M
Secretory proteins of Cryptosporidium parvumR21AI149309 · NIAID · WASHINGTON UNIVERSITY · PI SIBLEY, L. DAVID · 2020 to 2021
$448k
NIAID NIH HHS R01 AI145496NIAID NIH HHS R21 AI149309
6 · The paper itself

Abstract

The apicomplexan parasite

Indexed as

AnimalsCryptosporidiosisCryptosporidium parvumFecesFemaleGene DeletionImmunocompromised HostInsulysinInterferon gamma ReceptorLife Cycle StagesMiceMice, SCIDMicroscopy, ElectronOocystsPeptide HydrolasesReceptors, InterferonInsulysinInterferon gamma ReceptorPeptide HydrolasesReceptors, Interferonactive-site mutantCRISPR/Cas9cryptosporidiosisoocyst sheddingpathogenesissexual development

Identifiers

PMID33688009
PMCPMC8092296
OpenAlexW3135707257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.