Evidence map›Paper›PMID 33687768›Full record

ArticleBrain and behavior2021

Christmas, acute ischemic stroke and stroke-related mortality in Hungary.

András Folyovich, Réka Mátis, Nadim Al-Muhanna, Tamás Jarecsny, Eszter Dudás, Dorottya Jánoska, Mihály Pálosi, Anna K Béres-Molnár, Gergely Toldi

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

András FolyovichDepartment of Neurology and Stroke, Szent János Hospital, Budapest, Hungary.
Réka MátisFaculty of Public Governance and International Studies, University of Public Service, Budapest, Hungary.
Nadim Al-MuhannaDepartment of Neurology and Stroke, Szent János Hospital, Budapest, Hungary.
Tamás JarecsnyDepartment of Neurology and Stroke, Szent János Hospital, Budapest, Hungary.
Eszter DudásDepartment of Neurology and Stroke, Szent János Hospital, Budapest, Hungary.
Dorottya JánoskaDepartment of Neurology and Stroke, Szent János Hospital, Budapest, Hungary.
Mihály PálosiNational Health Insurance Fund, Budapest, Hungary.
Anna K Béres-MolnárDepartment of Neurology and Stroke, Szent János Hospital, Budapest, Hungary.
Gergely ToldiDepartment of Laboratory Medicine, Semmelweis University, Budapest, Hungary.ORCID 0000-0003-0178-1243
Szent János Kórház · HULudovika University of Public Service · HUNational Health Insurance Fund · RSSemmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesRisk factors for stroke include psychological effects, such as depression. Festive occasions (such as Christmas in Hungary) may carry a significant emotional impact and may therefore contribute to increased cardiovascular risk. Thrombolytic treatment of acute ischemic stroke has a narrow time window and allows for the precise assessment of stroke incidence. MATERIALS &

methodsWe analyzed anonymized national data of the number of thrombolytic treatments for acute ischemic stroke and the number of stroke-related deaths between 1 January 2007 and 31 December 2016 in Hungary within 2-day, 5-day, and 1-month periods preceding and following 24 December each year. Analysis of subgroups based on age (below and over 65 years) and sex was also performed.

resultsThe number of thrombolytic treatments was higher in all three periods preceding Christmas compared to the corresponding period that follows the feast. This increase was particularly prominent in men below 65 years of age. While overall stroke-associated mortality was increased 1 month after Christmas, the death rate was higher a month before rather than after Christmas in men below 65 years of age and in women both below and over 65 years of age 5 days before Christmas.

conclusionsThese findings may predominantly relate to emotional and psychological factors. In case of women, the anxiety secondary to festive preparations, while in men below 65 years, the increased psychological stress of providing financial security for the celebration may play an important role.

Indexed as

Brain IschemiaIschemic StrokeStrokeAgedChild, PreschoolFemaleHumansHungaryMaleThrombolytic Therapyanxietydeath shiftemotional impactstressthrombolysis

Identifiers

PMID33687768
PMCPMC8119813
OpenAlexW3135411028

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.