Trial reportCancer causes & control : CCC2021
The influence of multi-morbidities on colorectal cancer screening recommendations and completion.
Trial report in Cancer causes & control : CCC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01742065 (Strategies and Opportunities to Stop Colon Cancer in Priority Populations), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Strategies and Opportunities to Stop Colon Cancer in Priority Populations
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prevalence of comorbidity in the lung cancer screening population: A systematic review and meta-analysis.Journal of medical screening · 2023Pooled it
- A machine learning-based prediction model for colorectal liver metastasis.Clinical and experimental medicine · 2025Article
- Cervical cancer screening rates in females living with HIV at three healthcare settings in the United States, 2010-2019.Cancer causes & control : CCC · 2025Article
- Article
- Perceptions of the Impact of Comorbidity on the Bowel Cancer Screening Programme: Qualitative Study With Bowel Screening Participants and Staff.Health expectations : an international journal of public participation in health care and health policy · 2024Article
- Optimization of colorectal cancer screening strategies: New insights.World journal of gastroenterology · 2024Article
- Effectiveness of colonoscopy, immune fecal occult blood testing, and risk-graded screening strategies in colorectal cancer screening.World journal of gastrointestinal surgery · 2024Article
- Prediction and analysis of albumin-bilirubin score combined with liver function index and carcinoembryonic antigen on liver metastasis of colorectal cancer.World journal of gastrointestinal surgery · 2024Article
- Multi-morbidity and its association with common cancer diagnoses: a UK Biobank prospective study.BMC public health · 2023Article
- Commencing colorectal cancer screening at age 45 years in U.S. racial groups.Frontiers in oncology · 2022Article
- Rate and associated factors of refusal to perform immunochemical Faecal Occult Blood Test (iFOBT) among semi-urban communities.PloS one · 2021Article
- Cardiovascular Health and Colorectal Cancer Screening in Black Men: A Cross-Sectional Analysis.American journal of men's healthArticle
- Clinical Diagnosis Codes Identify Patients Unlikely to Receive Orders for Fecal Immunochemical Tests.Cancer control : journal of the Moffitt Cancer CenterObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposePatients' chronic disease burden can influence the likelihood that providers will recommend cancer screening and that patients will participate in it. Using data from the STOP CRC pragmatic study, we examined associations between chronic disease burden and colorectal cancer screening recommendation and use.
methodsParticipating STOP CRC clinics (n = 26) received either usual care or training to implement a mailed fecal immunochemical test (FIT) outreach program. Selected clinic patients (n = 60,187 patients) were aged 50-74 and overdue for colorectal cancer screening. We used logistic regression to examine the associations between FIT recommendations and completion and patients' chronic disease burden, calculated using the Charlson Comorbidity Index and the Chronic Illness and Disability Payment System.
resultsFor each index, FIT recommendation odds were 8-9% higher among individuals with minimal chronic disease burden and 13-23% lower among individuals with high chronic disease burden (inverted U-shaped association). Among adults who were ordered a FIT, FIT completion odds were 20% lower for individuals with any, versus no, chronic condition and diminished with increasing disease burden (inverse linear association).
conclusionsAnalysis showed an inverted U-shaped association between patients' chronic disease burden and providers' recommendation of a FIT and an inverse linear association between patients' chronic disease burden and FIT completion. ClinicalTrials.gov registration: NCT01742065.
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