Evidence map›Paper›PMID 33687251›Full record

ArticleThe Journal of chemical physics2020

Systematic investigation of synthetic polyelectrolyte bottlebrush solutions by neutron and dynamic light scattering, osmometry, and molecular dynamics simulation.

Ferenc Horkay, Alexandros Chremos, Jack F Douglas, Ronald L Jones, Junzhe Lou, Yan Xia

Abstract read
In one paragraph

Article in The Journal of chemical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ferenc HorkaySection on Quantitative Imaging and Tissue Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.ORCID 0000000325843613
Alexandros ChremosSection on Quantitative Imaging and Tissue Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.ORCID 0000000212543972
Jack F DouglasMaterials Science and Engineering Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA.ORCID 0000000172902300
Ronald L JonesMaterials Science and Engineering Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA.
Junzhe LouDepartment of Chemistry, Stanford University, Stanford, California 94305, USA.
Yan XiaDepartment of Chemistry, Stanford University, Stanford, California 94305, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a great interest in the synthesis and characterization of polyelectrolytes that mimic naturally occurring bottlebrush polyelectrolytes to capitalize on the unique properties of this class of macromolecules. Charged bottlebrush polymers form the protective mucus layer in the lungs, stomach, and orifices of animals and provide osmotic stabilization and lubrication to joints. In the present work, we systematically investigate bottlebrush poly(sodium acrylates) through a combination of measurements of solution properties (osmometry, small-angle neutron scattering, and dynamic light scattering) and molecular dynamics simulations, where the bottlebrush properties are compared in each case to their linear polymer counterparts. These complementary experimental and computational methods probe vastly different length- and timescales, allowing for a comprehensive characterization of the supermolecular structure and dynamics of synthetic polyelectrolyte bottlebrush molecules in solution.

Identifiers

PMID33687251
PMCPMC7252672

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.