SynthesisJournal of the American Heart Association2021
Reoperative Mitral Surgery Versus Transcatheter Mitral Valve Replacement: A Systematic Review.
Synthesis in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Transcatheter Mitral Valve Repair for Failed Surgical Mitral Valve Repair: A Systematic Review and Meta-Analysis.Reviews in cardiovascular medicine · 2022Pooled it
- Transcatheter mitral valve replacement versus redo surgery for mitral prosthesis failure: A systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Reoperative Mitral Surgery Versus Transcatheter Mitral Valve Replacement: A Systematic Review.Journal of the American Heart Association · 2021Pooled it
- Surgical and Transcatheter Approach of a Failed Mitral Valve Repair: A Comprehensive Review on Selecting the Most Suitable Approach.Journal of clinical medicine · 2026Review
- Transcatheter Mitral Valve Replacement in Failed Mitral Bioprosthesis: Case Report.Case reports in cardiology · 2026Article
- Clinical and subclinical acute brain injury caused by invasive cardiovascular procedures.Nature reviews. Cardiology · 2025Review
- Severe Mitral Stenosis and Regurgitation Due to Bioprosthetic Valve Failure with Massive Pannus.Surgical case reports · 2025Article
- Expanding treatment horizons: transcatheter mitral valve-in-valve replacement in bridging to heart transplant.Indian journal of thoracic and cardiovascular surgery · 2024Article
- Valve-in-Valve Transcatheter Mitral Valve Replacement in a Very High-Risk Octagenerian Patient: A Case Report.Cureus · 2024Article
- Transcatheter mitral valve-in-valve explant: Lessons learned.JTCVS techniques · 2024Article
- Early and long-term outcomes following redo mitral valve surgery in patients with prior minimally invasive mitral valve surgery.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Trans-catheter mitral valve-in-valve replacement in a patient on venoarterial extracorporeal membrane oxygenation: a case report.European heart journal. Case reports · 2023Article
- Redo hybrid mitral valve-in-valve for early structural valve degeneration: Pearls and pitfalls of a novel technique.JTCVS techniques · 2023Article
- 2021 ESC/EACTS Guidelines for the management of valvular heart disease.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022Article
- Direct access hybrid transatrial implantation of a Sapien 3 valve inside a bioprosthetic mitral valve with concomitant tricuspid valve replacement and cryoablation.Annals of cardiothoracic surgery · 2021Article
- Access options for transcatheter mitral valve implantation in patients with prior surgical bioprosthesis.Annals of cardiothoracic surgery · 2021Article
- Mitral Valve Annuloplasty Failure and Percutaneous Treatment Options.Current cardiology reports · 2021Review
- Transcatheter Valve-in-Valve Procedures for Bioprosthetic Valve Dysfunction in Patients With Rheumatic vs. Non-Rheumatic Valvular Heart Disease.Frontiers in cardiovascular medicine · 2021Article
- Article
- Mitral Valve-in-Valve Versus Repeat Surgical Mitral Valve Replacement in Patients With Failed Mitral Bioprostheses.Journal of the Society for Cardiovascular Angiography & InterventionsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bioprosthetic mitral structural valve degeneration and failed mitral valve repair (MVr) have traditionally been treated with reoperative mitral valve surgery. Transcatheter mitral valve-in-valve (MVIV) and valve-in-ring (MVIR) replacement are now feasible, but data comparing these approaches are lacking. We sought to compare the outcomes of (1) reoperative mitral valve replacement (redo-MVR) and MVIV for structural valve degeneration, and (2) reoperative mitral valve repair (redo-MVr) or MVR and MVIR for failed MVr. A literature search of PubMed, Embase, and the Cochrane Library was conducted up to July 31, 2020. Thirty-two studies involving 25 832 patients were included. Redo-MVR was required in ≈35% of patients after index surgery at 10 years, with 5% to 15% 30-day mortality. MVIV resulted in >95% procedural success with 30-day and 1-year mortality of 0% to 8% and 11% to 16%, respectively. Recognized complications included left ventricular outflow tract obstruction (0%-6%), valve migration (0%-9%), and residual regurgitation (0%-6%). Comparisons of redo-MVR and MVIV showed no statistically significant differences in mortality (11.3% versus 11.9% at 1 year,
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