Evidence map›Paper›PMID 33686866›Full record

SynthesisJournal of the American Heart Association2021

Angiographic Patency of Coronary Artery Bypass Conduits: A Network Meta-Analysis of Randomized Trials.

Mario Gaudino, Irbaz Hameed, N Bryce Robinson, Yongle Ruan, Mohamed Rahouma, Ajita Naik, Viola Weidenmann, Michelle Demetres, Derrick Y Tam, David L Hare and 3 more

Abstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Evidence for a Clinically Meaningful Effect of no-Touch Harvesting Technique on Vein Graft Patency-A Bayesian Reanalysis of the SWEDEGRAFT Trial.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  9. Observational
  10. Article
  11. No-Touch Saphenous Vein Graft for Coronary Artery Bypass Grafting.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2025
    Review
  12. Review
  13. Conduits and Strategies for Arterial Revascularization in CABG.Reviews in cardiovascular medicine · 2023
    Review
  14. Is the COMPASS pointing towards clinical equipoise for the right internal mammary artery?Indian journal of thoracic and cardiovascular surgery · 2023
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mario GaudinoDepartment of Cardiothoracic Surgery Weill Cornell Medicine New York NY.
Irbaz HameedDepartment of Cardiothoracic Surgery Weill Cornell Medicine New York NY.
N Bryce RobinsonDepartment of Cardiothoracic Surgery Weill Cornell Medicine New York NY.
Yongle RuanDepartment of Cardiothoracic Surgery Weill Cornell Medicine New York NY.
Mohamed RahoumaDepartment of Cardiothoracic Surgery Weill Cornell Medicine New York NY.
Ajita NaikDepartment of Cardiothoracic Surgery Weill Cornell Medicine New York NY.
Viola WeidenmannDepartment of Cardiothoracic Surgery Weill Cornell Medicine New York NY.
Michelle DemetresSamuel J. Wood Library and C.V. Starr Biomedical Information Centre, Weill Cornell Medicine New York NY.
Derrick Y TamSchulich Heart Centre Sunnybrook Health Science University of Toronto Toronto Ontario Canada.
David L HareDepartment of Cardiology Austin Health Melbourne Australia.
Leonard N GirardiDepartment of Cardiothoracic Surgery Weill Cornell Medicine New York NY.
Giuseppe Biondi-ZoccaiDepartment of Medico-Surgical Sciences and Biotechnologies Sapienza University Rome Italy.
Stephen E FremesSchulich Heart Centre Sunnybrook Health Science University of Toronto Toronto Ontario Canada.

Funding

CIHR
6 · The paper itself

Abstract

Background Several randomized trials have compared the patency of coronary artery bypass conduits. All of the published studies, however, have performed pairwise comparisons and a comprehensive evaluation of the patency rates of all conduits has yet to be published. We set out to investigate the angiographic patency rates of all conduits used in coronary bypass surgery by performing a network meta-analysis of the current available randomized evidence. Methods and Results A systematic literature search was conducted for randomized controlled trials comparing the angiographic patency rate of the conventionally harvested saphenous vein, the no-touch saphenous vein, the radial artery (RA), the right internal thoracic artery, or the gastroepiploic artery. The primary outcome was graft occlusion. A total of 4160 studies were retrieved of which 14 were included with 3651 grafts analyzed. The weighted mean angiographic follow-up was 5.1 years. Compared with the conventionally harvested saphenous vein, both the RA (incidence rate ratio [IRR] 0.54; 95% CI, 0.35-0.82) and the no-touch saphenous vein (IRR 0.55; 95% CI, 0.39-0.78) were associated with lower graft occlusion. The RA ranked as the best conduit (rank score for RA 0.87 versus 0.85 for no-touch saphenous vein, 0.23 for right internal thoracic artery, 0.29 for gastroepiploic artery, and 0.25 for the conventionally harvested saphenous vein). Conclusions Compared with the conventionally harvested saphenous vein, only the RA and no-touch saphenous vein grafts are associated with significantly lower graft occlusion rates. The RA ranks as the best conduit. Registration URL: https://www.crd.york.ac.uk/prospero; Unique identifier: CRD42020164492.

Indexed as

Vascular PatencyCoronary AngiographyCoronary Artery BypassCoronary Artery DiseaseHumansMammary ArteriesRandomized Controlled Trials as TopicSaphenous Veincoronary artery bypasscoronary artery bypass graftcoronary artery disease

Identifiers

PMID33686866
PMCPMC8174193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.