Evidence map›Paper›PMID 33686816›Full record

ArticleKorean journal of radiology2021

Regional Amyloid Burden Differences Evaluated Using Quantitative Cardiac MRI in Patients with Cardiac Amyloidosis.

Jin Young Kim, Yoo Jin Hong, Kyunghwa Han, Hye Jeong Lee, Jin Hur, Young Jin Kim, Byoung Wook Choi

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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  5. Echocardiographic red flags of ATTR cardiomyopathy a single centre validation.European heart journal. Imaging methods and practice · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jin Young KimDepartment of Radiology, Keimyung University School of Medicine, Daegu, Korea.ORCID 0000-0001-6714-8358
Yoo Jin HongDepartment of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University Medical Center, Seoul, Korea. uzzin@yuhs.ac.ORCID 0000-0002-7276-0944
Kyunghwa HanDepartment of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University Medical Center, Seoul, Korea.ORCID 0000-0002-5687-7237
Hye Jeong LeeDepartment of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University Medical Center, Seoul, Korea.ORCID 0000-0003-4349-9174
Jin HurDepartment of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University Medical Center, Seoul, Korea.ORCID 0000-0002-8651-6571
Young Jin KimDepartment of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University Medical Center, Seoul, Korea.ORCID 0000-0002-6235-6550
Byoung Wook ChoiDepartment of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University Medical Center, Seoul, Korea.ORCID 0000-0002-8873-5444
Severance Hospital · KRKeimyung University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate the regional amyloid burden and myocardial deformation using T1 mapping and strain values in patients with cardiac amyloidosis (CA) according to late gadolinium enhancement (LGE) patterns. MATERIALS AND

methodsForty patients with CA were divided into 2 groups per LGE pattern, and 15 healthy subjects were enrolled. Global and regional native T1 and T2 mapping, extracellular volume (ECV), and cardiac magnetic resonance (CMR)-feature tracking strain values were compared in an intergroup and interregional manner.

resultsOf the patients with CA, 32 had diffuse global LGE (group 2), and 8 had focal patchy or no LGE (group 1). Global native T1, T2, and ECV were significantly higher in groups 1 and 2 than in the control group (native T1: 1384.4 ms vs. 1466.8 ms vs. 1230.5 ms; T2: 53.8 ms vs. 54.2 ms vs. 48.9 ms; and ECV: 36.9% vs. 51.4% vs. 26.0%, respectively; all,

conclusionQuantitative T1 mapping parameters such as native T1 and ECV may help diagnose early CA. ECV, in particular, can reflect regional differences in the amyloid deposition in patients with advanced CA, and increased basal ECV is related to decreased basal strain. Therefore, quantitative CMR parameters may help diagnose CA and determine its severity in patients with or without LGE.

Indexed as

AmyloidosisCardiomyopathiesAdultAgedContrast MediaFemaleGadoliniumHumansMagnetic Resonance ImagingMagnetic Resonance Imaging, CineMaleMiddle AgedMyocardiumPredictive Value of TestsProspective StudiesVentricular Function, LeftContrast MediaGadoliniumExtracellular spaceFeature trackingHeartMagnetic resonance imagingMappingMyocardium

Identifiers

PMID33686816
PMCPMC8154779
OpenAlexW3134219504

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.