ArticleJournal of diabetes investigation2021
Falls and fractures associated with type 2 diabetic polyneuropathy: A cross-sectional nationwide questionnaire study.
Article in Journal of diabetes investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 1 citations in OpenAlex.
- A Systematic Review Examining the Association of Falls With Diabetes-Related Foot Ulcers.Journal of foot and ankle research · 2025Pooled it
- Exploring the exercise for enhancing postural control, gait, and muscle strength in older adults with diabetic peripheral neuropathy: a systematic review and meta-analysis.Frontiers in aging · 2025Pooled it
- Effectiveness of exercise on musculoskeletal function and clinical outcomes in patients with diabetic peripheral neuropathy: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022Guideline
- Mechanistic Pathways Linking Type 2 Diabetes Mellitus, Hypertension, and Osteoarthritis to Falls in Older Adults: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Direct Peroneal and Tibial Transcutaneous Electrical Nerve Stimulation for Improving Postural Control in European Women with Diabetic Polyneuropathy: A Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Type 1 diabetes, ageing and frailty: an underexplored intersection.Diabetologia · 2026Review
- Effectiveness of various exercise types in reducing fall risk among older adults with diabetic peripheral neuropathy: A systematic review and meta-analysis.Journal of exercise science and fitness · 2025Review
- Salivary 1,5-Anhydroglucitol and AGEs Are Associated with Postural Instability in Diabetic Foot Patients.Medicina (Kaunas, Lithuania) · 2025Article
- Nonlinear associations between METS-IR and all-cause as well as cardiovascular mortality in adults with osteoporosis and osteopenia: evidence from NHANES 2007-2023.Scientific reports · 2025Article
- Peripheral neuropathy, an independent risk factor for falls in the elderly, impairs stepping as a postural control mechanism: A case-cohort study.Journal of the peripheral nervous system : JPNS · 2024Article
- Psychosocial Care for People With Diabetic Neuropathy: Time for Action.Diabetes care · 2024Review
- The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Project Cohort and Biobank from 2010 Through 2023-A Cohort Profile Update.Clinical epidemiology · 2024Article
- Nerve conduction velocity is independently associated with bone mineral density in type 2 diabetes mellitus.Frontiers in endocrinology · 2023Article
- Weight Loss Interventions and Skeletal Health in Persons with Diabetes.Current osteoporosis reports · 2022Review
- Fracture Patterns in Type 1 and Type 2 Diabetes Mellitus: A Narrative Review of Recent Literature.Current osteoporosis reports · 2021Review
- Falls and fractures associated with type 2 diabetic polyneuropathy: A cross-sectional nationwide questionnaire study.Journal of diabetes investigation · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
AIMS/
introductionTo examine the prevalence of falls and fractures, and the association with symptoms of diabetic polyneuropathy (DPN) in patients with recently diagnosed type 2 diabetes. MATERIALS AND
methodsA detailed questionnaire on neuropathy symptoms and falls was sent to 6,726 patients enrolled in the Danish Center for Strategic Research in Type 2 Diabetes cohort (median age 65 years, diabetes duration 4.6 years). Complete data on fractures and patient characteristics were ascertained from population-based health registries. We defined possible DPN as a score ≥4 on the Michigan Neuropathy Screening Instruments questionnaire. Using Poisson regression analyses, we estimated the adjusted prevalence ratio (aPR) of falls and fractures, comparing patients with and without DPN.
resultsIn total, 5,359 patients (80%) answered the questions on the Michigan Neuropathy Screening Instruments questionnaire and falls. Within the year preceding the questionnaire response, 17% (n = 933) reported at least one fall and 1.4% (n = 76) suffered from a fracture. The prevalence ratio of falls was substantially increased in patients with possible DPN compared with those without (aPR 2.33, 95% confidence interval [CI] 2.06-2.63). The prevalence ratio increased with the number of falls from aPR 1.51 (95% CI 1.22-1.89) for one fall to aPR 5.89 (95% CI 3.84-9.05) for four or more falls within the preceding year. Possible DPN was associated with a slightly although non-significantly increased risk of fractures (aPR 1.32, 95% CI 0.75-2.33).
conclusionsPatients with recently diagnosed type 2 diabetes and symptoms of DPN had a highly increased risk of falling. These results emphasize the need for preventive interventions to reduce fall risk among patients with type 2 diabetes and possible DPN.
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