Evidence map›Paper›PMID 33686513›Full record

ReviewCurrent cardiology reports2021

Evolution and Outcomes of Premature Coronary Artery Disease.

Cara Lea Smith, Matthew Seigerman, Srinath Adusumalli, Jay Giri, Paul N Fiorilli, Daniel M Kolansky, Taisei Kobayashi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cara Lea SmithDepartment of Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Matthew SeigermanDivision of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Srinath AdusumalliDivision of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Jay GiriDivision of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Paul N FiorilliDivision of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Daniel M KolanskyDivision of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Taisei KobayashiDivision of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA. Taisei.Kobayashi@pennmedicine.upenn.edu.ORCID 0000-0002-3081-6225

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to explore the evolution and outcomes of premature coronary artery disease (PCAD) while reviewing strategies for effective screening of those at high risk for developing this disease. RECENT

findingsPremature coronary artery disease (PCAD) affects a population of patients not typically identified as high risk by current risk stratification guidelines or traditional risk calculation tools. Not only does PCAD represent a large proportion of overall cardiovascular disease, it also afflicts a population in which the rate of mortality from cardiovascular disease has plateaued despite an overall declining population-wide cardiovascular mortality rate. There is ample opportunity for behavioral change strategies, screening tools, adapted imaging modalities, and precision pharmacotherapies to be more precisely targeted toward those at highest risk for premature coronary artery disease. Premature coronary artery disease (PCAD) is pervasive and not frequently represented within contemporary risk calculation models. Providers should pursue proactive screening and aggressive risk factor modification and deploy appropriate preventative therapies in caring for younger populations.

Indexed as

Cardiovascular DiseasesCoronary Artery DiseaseHumansRisk FactorsPremature coronary artery diseaseRisk modificationRisk stratification

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.