ArticleThe Journal of heredity2021
Limited Evidence for Parallel Evolution Among Desert-Adapted Peromyscus Deer Mice.
Article in The Journal of heredity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- INSIG1 parallel substitution drives lipid/sterol metabolic plasticity mediating desert adaptation in ungulates.Communications biology · 2026Article
- A high-quality genome assembly for a desert-adapted rodent, Merriam's kangaroo rat (Dipodomys merriami).The Journal of heredity · 2025Article
- High total water loss driven by low-fat diet in desert-adapted mice.Journal of mammalogy · 2025Article
- Impacts of dietary fat on multi tissue gene expression in the desert-adapted cactus mouse.The Journal of experimental biology · 2024Article
- The multi-tissue gene expression and physiological responses of water deprived Peromyscus eremicus.BMC genomics · 2024Article
- When the tap runs dry: The multi-tissue gene expression and physiological responses of water deprivedbioRxiv : the preprint server for biology · 2024Article
- When the tap runs dry: the physiological effects of acute experimental dehydration in Peromyscus eremicus.The Journal of experimental biology · 2023Article
- Whole-genome sequencing reveals adaptations of hairy-footed jerboas (Dipus, Dipodidae) to diverse desert environments.BMC biology · 2023Article
- When the tap runs dry: The physiological effects of acute experimental dehydration inbioRxiv : the preprint server for biology · 2023Article
- Similar adaptative mechanism but divergent demographic history of four sympatric desert rodents in Eurasian inland.Communications biology · 2023Article
- Chromosome size affects sequence divergence between species through the interplay of recombination and selection.Evolution; international journal of organic evolution · 2022Article
- Disentangling environmental drivers of circadian metabolism in desert-adapted mice.The Journal of experimental biology · 2021Article
- Life in Deserts: The Genetic Basis of Mammalian Desert Adaptation.Trends in ecology & evolution · 2021Review
- Multiple Routes to Animal Consciousness: Constrained Multiple Realizability Rather Than Modest Identity Theory.Frontiers in psychology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
Warming climate and increasing desertification urge the identification of genes involved in heat and dehydration tolerance to better inform and target biodiversity conservation efforts. Comparisons among extant desert-adapted species can highlight parallel or convergent patterns of genome evolution through the identification of shared signatures of selection. We generate a chromosome-level genome assembly for the canyon mouse (Peromyscus crinitus) and test for a signature of parallel evolution by comparing signatures of selective sweeps across population-level genomic resequencing data from another congeneric desert specialist (Peromyscus eremicus) and a widely distributed habitat generalist (Peromyscus maniculatus), that may be locally adapted to arid conditions. We identify few shared candidate loci involved in desert adaptation and do not find support for a shared pattern of parallel evolution. Instead, we hypothesize divergent molecular mechanisms of desert adaptation among deer mice, potentially tied to species-specific historical demography, which may limit or enhance adaptation. We identify a number of candidate loci experiencing selective sweeps in the P. crinitus genome that are implicated in osmoregulation (Trypsin, Prostasin) and metabolic tuning (Kallikrein, eIF2-alpha kinase GCN2, APPL1/2), which may be important for accommodating hot and dry environmental conditions.
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