ArticleFrontiers in oncology2021
The Role of Real-Time Contrast-Enhanced Ultrasound in Guiding Radiofrequency Ablation of Reninoma: Case Report and Literature Review.
Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Reninoma in an adolescent boy with negative selective renal vein sampling: a case report and review of the literature.Frontiers in endocrinology · 2026Review
- Reninoma: A Rare Cause of Surgically Curable Hypertension and Secondary Hyperaldosteronism.Journal of the ASEAN Federation of Endocrine Societies · 2025Article
- Surgical Curative Approach for Severe Hypertension in Select Patients With Underrecognized Rare Renal Tumors: A Case Report.Case reports in urology · 2025Article
- How to identify juxtaglomerular cell tumor by ultrasound: a case series and review of the literature.BMC medical imaging · 2024Review
- Value of CEUS combined with feeding artery ablation in the microwave ablation of large solid benign thyroid nodules.European radiology · 2023Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReninoma is a rare renal endocrine tumor that can cause secondary hypertension, characterized by hypertension, hypokalemia, high renin and aldosterone with normal aldosterone renin ratio (ARR), and occurs more in young female. Mainstream treatment option is surgery, but is less suitable for small or deep lesions, which makes ablation a promising alternative. CASE PRESENTATION: Two young female with typical manifestations of reninoma, including hypertension, hypokalemia, high renin, high aldosterone and normal ARR, were treated successfully with real-time contrast-enhanced ultrasound guided radiofrequency ablation, and contrast-enhanced ultrasound was also performed before and after treatment for diagnosis and postoperative assessment. Afterward, their blood pressure and laboratory tests became normal and remained steady during the follow-up of 32 and 6 months, respectively.
conclusionContrast-enhanced ultrasound guided radiofrequency ablations is a promising alternative for reninoma treatment with comparable safety and efficacy with surgery, and has advantages especially in small or deep lesions.
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Registered trials
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