Evidence map›Paper›PMID 33685983›Full record

ArticleJournal of neurointerventional surgery2022

Value of repeated imaging in patients with a stroke who are transferred for endovascular treatment.

Laura C C van Meenen, Nerea Arrarte Terreros, Adrien E Groot, Manon Kappelhof, Ludo F M Beenen, Henk A Marquering, Bart J Emmer, Yvo B W E M Roos, Charles B L M Majoie, Jonathan M Coutinho

Abstract read
In one paragraph

Article in Journal of neurointerventional surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Laura C C van MeenenDepartment of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, North Holland, The Netherlands.
Nerea Arrarte TerrerosDepartment of Biomedical Engineering and Physics, Amsterdam UMC, University of Amsterdam, Amsterdam, North Holland, The Netherlands.
Adrien E GrootDepartment of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, North Holland, The Netherlands.
Manon KappelhofDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, North Holland, The Netherlands.
Ludo F M BeenenDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, North Holland, The Netherlands.
Henk A MarqueringDepartment of Biomedical Engineering and Physics, Amsterdam UMC, University of Amsterdam, Amsterdam, North Holland, The Netherlands.
Bart J EmmerDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, North Holland, The Netherlands.
Yvo B W E M RoosDepartment of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, North Holland, The Netherlands.
Charles B L M MajoieDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, North Holland, The Netherlands.
Jonathan M CoutinhoDepartment of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, North Holland, The Netherlands j.coutinho@amsterdamumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with a stroke who are transferred to a comprehensive stroke center for endovascular treatment (EVT) often undergo repeated neuroimaging prior to EVT.

objectiveTo evaluate the yield of repeating imaging and its effect on treatment times.

methodsWe included adult patients with a large vessel occlusion (LVO) stroke who were referred to our hospital for EVT by primary stroke centers (2016-2019). We excluded patients who underwent repeated imaging because primary imaging was unavailable, incomplete, or of insufficient quality. Outcomes included treatment times and repeated imaging findings.

resultsOf 677 transferred LVO stroke, 551 were included. Imaging was repeated in 165/551 patients (30%), mostly because of clinical improvement (86/165 (52%)) or deterioration (40/165 (24%)). Patients who underwent repeated imaging had higher door-to-groin-times than patients without repeated imaging (median 43 vs 27 min, adjusted time difference: 20 min, 95% CI 15 to 25). Among patients who underwent repeated imaging because of clinical improvement, the LVO had resolved in 50/86 (58%). In patients with clinical deterioration, repeated imaging led to refrainment from EVT in 3/40 (8%). No symptomatic intracranial hemorrhages (sICH) were identified. Ultimately, 75/165 (45%) of patients with repeated imaging underwent EVT compared with 326/386 (84%) of patients without repeated imaging (p<0.01).

conclusionsNeuroimaging was repeated in 30% of patients with an LVO stroke and resulted in a median treatment delay of 20 minutes. In patients with clinical deterioration, no sICH were detected and repeated imaging rarely changed the indication for EVT. However, in more than half of patients with clinical improvement, the LVO had resolved, resulting in refrainment from EVT.

Indexed as

Brain IschemiaEndovascular ProceduresStrokeAdultHumansIntracranial HemorrhagesThrombectomyTime-to-TreatmentTreatment OutcomeCTstrokethrombectomy

Identifiers

PMID33685983
PMCPMC8784993

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.