Trial reportAnnals of family medicine
Scaling Up Patient-Centered Interdisciplinary Care for Multimorbidity: A Pragmatic Mixed-Methods Randomized Controlled Trial.
Trial report in Annals of family medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 8 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Effectiveness and Experiences of Self-Management Interventions in Adults With Multiple Long-Term Conditions: A Mixed Methods Systematic Review.Journal of evaluation in clinical practice · 2026Pooled it
- Effectiveness of interventions for the management of multimorbidity in primary care and community settings: systematic review and meta-analysis.Family practice · 2025Pooled it
- Effects of multidisciplinary teamwork in non-hospital settings on healthcare and patients with chronic conditions: a systematic review and meta-analysis.BMC primary care · 2025Pooled it
- Reporting and representation of underserved groups in intervention studies for patients with multiple long-term conditions: a systematic review.Journal of the Royal Society of Medicine · 2024Pooled it
- Influence of health-system change on treatment burden: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023Pooled it
- Pooled it
- A systematic review of impact of person-centred interventions for serious physical illness in terms of outcomes and costs.BMJ open · 2022Pooled it
- Effects of goal-oriented care for adults with multimorbidity: A systematic review and meta-analysis.Journal of evaluation in clinical practice · 2022Pooled it
- The Health and Life in Balance intervention to improve patient capacity for older people with multimorbidity: a pragmatic mixed methods non-randomised pilot study.BMC primary care · 2025Trial
- Patient-centred innovation for multimorbidity care: a mixed-methods, randomised trial and qualitative study of the patients' experience.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Trial
- Trial
- Review
- Patient-Centred Care for Multimorbid Patients: A Scoping Review.Journal of clinical medicine · 2026Review
- Evidence-based nursing interventions in hepatocellular carcinoma care.Discover oncology · 2026Article
- Community-based management strategies for adults with multimorbidity: a systematic review of clinical and patient-centred outcomes.BMJ public health · 2026Article
- Multimorbidity Management: A Scoping Review of Interventions and Health Outcomes.International journal of environmental research and public health · 2025Article
- Economic burdens of health expenditure for multi-morbidity of older people with hypertension in China and Vietnam.Frontiers in public health · 2025Article
- Assessing the impact of Canadian primary care research and researchers: Citation analysis.Canadian family physician Medecin de famille canadien · 2024Article
- Optimizing clinical nutrition research: the role of adaptive and pragmatic trials.European journal of clinical nutrition · 2023Review
- Challenges in Multimorbidity Research: Lessons Learned From the Most Recent Randomized Controlled Trials in Primary Care.Frontiers in medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo measure the effectiveness of a 4-month interdisciplinary multifaceted intervention based on a change in care delivery for patients with multimorbidity in primary care practices.
methodsA pragmatic randomized controlled trial with a mixed-methods design in patients aged 18 to 80 years with 3 or more chronic conditions from 7 family medicine groups (FMGs) in Quebec, Canada. Health care professionals (nurses, nutritionists, kinesiologists) from the FMGs were trained to deliver the patient-centered intervention based on a motivational approach and self-management support. Primary outcomes: self-management (Health Education Impact Questionnaire); and self-efficacy. SECONDARY OUTCOMES: health status, quality of life, and health behaviors. Quantitative analyses used multi-level mixed effects and generalized linear mixed models controlling for clustering within FMGs. We also conducted in-depth interviews with patients, family members, and health care professionals.
resultsThe trial randomized 284 patients (144 in intervention group, 140 in control group). The groups were comparable. After 4 months, the intervention showed a neutral effect for the primary outcomes. There was significant improvement in 2 health behaviors (healthy eating with odds ratios [OR] 4.36;
conclusionsQuantitatively, this intervention showed a neutral effect on the primary outcomes and substantial improvement in 2 health behaviors as secondary outcomes. Qualitatively, the intervention was evaluated as positive. The combination of qualitative and quantitative designs proved to be a good design for evaluating this complex intervention.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.