Evidence map›Paper›PMID 33685522›Full record

ArticleJournal of eating disorders2021

The Maudsley model of anorexia nervosa treatment for adolescents and young adults (MANTRa): a study protocol for a multi-center cohort study.

Tanja Wittek, Stefanie Truttmann, Michael Zeiler, Julia Philipp, Ellen Auer-Welsbach, Doris Koubek, Susanne Ohmann, Sonja Werneck-Rohrer, Petra Sackl-Pammer, Gabriele Schöfbeck and 5 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of eating disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03535714 (MANTR-a), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03535714 naunknown statusnot on this map

MANTR-a: Evaluation of a Therapeutic Intervention for Adolescents and Young Adults With Anorexia Nervosa

TypeinterventionalSponsorMedical University of ViennaRan2018 to 2022Enrolled100ConditionsAnorexia Nervosa, AnorexiaArmsMANTR-a treatment
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Oxytocin Amplifies Negative Response to Ambiguity in Adolescent Females With and Without Eating Disorders.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Trial
  3. Trial
  4. Article
  5. Observational
  6. Family therapy for emerging adults with anorexia nervosa: Expert opinion on evidence, practice considerations, and future directions.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Review
  7. Article
  8. The Maudsley model of anorexia nervosa treatment for adolescents and emerging adults: A multi-centre cohort study.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Article
  9. Alexithymia and Emotion Recognition Over the Treatment Course in Adolescents and Emerging Adults With Anorexia Nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Article
  10. Article
  11. Exploring neurocognitive features in adolescents and young adults with anorexia nervosa: Evidence from a longitudinal study.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Tanja WittekDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, 1090, Vienna, Austria.
Stefanie TruttmannDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, 1090, Vienna, Austria.
Michael ZeilerDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, 1090, Vienna, Austria.
Julia PhilippDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, 1090, Vienna, Austria.
Ellen Auer-WelsbachDepartment of Neurology and Psychiatry of Childhood and Adolescence, Clinical Center Klagenfurt, 9020, Klagenfurt am Wörthersee, Austria.
Doris KoubekMedical Practice for Child and Adolescent Psychiatry, 4020, Linz, Austria.
Susanne OhmannDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, 1090, Vienna, Austria.
Sonja Werneck-RohrerDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, 1090, Vienna, Austria.
Petra Sackl-PammerDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, 1090, Vienna, Austria.
Gabriele SchöfbeckDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, 1090, Vienna, Austria.
Dunja MairhoferDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, 1090, Vienna, Austria.
Leonie KahlenbergDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, 1090, Vienna, Austria.
Ulrike SchmidtInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, WC2R 21S, UK.
Andreas F K KarwautzDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, 1090, Vienna, Austria.
Gudrun WagnerDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, 1090, Vienna, Austria. gudrun.wagner@meduniwien.ac.at.ORCID http://orcid.org/0000-0002-4845-9684
Medical University of Vienna · ATKing's College London · GBUniversity of Klagenfurt · AT

Funding

Gemeinsame Gesundheitsziele aus dem Rahmen-Pharmavertrag/Pharma Master Agreement (AT) 99901006800
6 · The paper itself

Abstract

backgroundThe treatment of anorexia nervosa (AN) is often challenging due to medical complications as well as high relapse and mortality rates. Studies about effective treatment options for people with AN are particularly scarce in the adolescent population. This paper is a study protocol for a multi-center cohort study assessing the feasibility, acceptability and efficacy of a new, manualized treatment program, the "Maudsley Model of Anorexia Nervosa Treatment for Adolescents and Young Adults" (MANTRa) compared to psychotherapeutic treatment as usual (TAU). METHODS/

designOne hundred patients between 13 and 21 years who meet the inclusion criteria will receive 24 to 34 individual weekly MANTRa therapy sessions or weekly TAU sessions. Primary outcome variables will be BMI and eating disorder psychopathology 12 months after baseline. Further changes in central coherence, cognitive flexibility, emotion recognition, comorbid psychopathology (e.g. depression, obsessive-compulsive and anxiety disorders, non-suicidal self-injury), personality factors and therapeutic alliance will be assessed. DISCUSSION: This multi-center study will examine the utility of the treatment program MANTRa for adolescents with AN and, therefore enhances the current knowledge about potential treatments for this patient group.

trial registrationClinicalTrials.gov Identifier: NCT03535714 . Registered: 24/05/2018 (retrospectively registered, still recruiting).

Indexed as

AdolescentsAnorexia nervosaMANTRaMaudsley modelPsychotherapyStudy protocolTreatmentYoung adults

Identifiers

PMID33685522
PMCPMC7941930
OpenAlexW3135433649

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.