Evidence map›Paper›PMID 33685092›Full record

ArticleZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2021

[Research progress of neural precursor cells-expressed developmentally down-regulated protein-8 in liver diseases].

J Sun, D Y Zhang, J Wang, Y Y Lu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

J SunComprehensive Liver Cancer Center, 5th Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
D Y ZhangComprehensive Liver Cancer Center, 5th Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
J WangInstitute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Academy of Military Sciences, Beijing 100850, China.
Y Y LuComprehensive Liver Cancer Center, 5th Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Academy of Military Medical Sciences · CN

Funding

National Major Scientific and Technological Special Project for "Significant New Drugs Development" 2018ZX09J18107-004National Natural Science Foundation of China 81672368Natural Science Foundation of Beijing 7172207
6 · The paper itself

Abstract

Neural precursor cells-expressed developmentally down-regulated protein-8 (NEDD8) is one of the important members of the ubiquitin family, which plays an important role in maintaining cell stability, cell cycle regulation, signal transduction, transcription, and translation, DNA repair, and tumorigenesis through covalently bound substrates (also known as neddylation modification). In recent years, studies have found that the dysfunction of NEDD8 and its related enzymes is common in liver diseases, and is widely involved in the biological processes of hepatitis, liver fibrosis, proliferation, invasion, apoptosis and autophagy of liver cancer cells. This article focuses on the research progress of NEDD8 in liver diseases.

Indexed as

Neural Stem CellsApoptosisHumansLiver CirrhosisSignal TransductionUbiquitinUbiquitinHepatocellular carcinomaLiver diseasesNeddylationNeural precursor cell-expressed developmentally downregulated 8

Identifiers

PMID33685092
PMCPMC12814468
OpenAlexW3134930953

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.