Evidence map›Paper›PMID 33684539›Full record

ArticleThe journal of pain2021

Gender Biases in Estimation of Others' Pain.

Lanlan Zhang, Elizabeth A Reynolds Losin, Yoni K Ashar, Leonie Koban, Tor D Wager

Open access · bronzeAbstract read
In one paragraph

Article in The journal of pain, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 4 pooled it
34.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 4 syntheses or guidelines pooled it, 291 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The role of exercise for pain management in adults living with and beyond cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  4. Pooled it
  5. TheWestern journal of nursing research · 2025
    Trial
  6. Trial
  7. Article
  8. Missed opportunities: delayed in-hospital palliative care consultations in patients with non-metastatic cancers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  9. Article
  10. Gender-Based Differences in Arthroplasty Utilization Across Two Tertiary Academic Centers.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
    Article
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. The Critical Care Pain Observation Tool for Families (CPOT-Fam).Canadian journal of pain = Revue canadienne de la douleur · 2026
    Article
  20. Review

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Lanlan ZhangSchool of Leisure Sport and Management, Guangzhou Sport University, Guangzhou, China.
Elizabeth A Reynolds LosinDepartment of Psychology, University of Miami, Miami, Florida.
Yoni K AsharDepartment of Psychiatry, Weill Cornell Medical College, New York, New York.
Leonie KobanParis Brain Institute, Paris, France.
Tor D WagerDepartment of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire. Electronic address: Tor.D.Wager@Dartmouth.edu.
Cornell University · USDartmouth College · USGuangzhou Sport University · CNInstitut du Cerveau · FRUniversity of Miami · US

Funding

The Neural Bases of Placebo Effects and their Relation to Regulatory ProcessesR01MH076136 · NIMH · UNIVERSITY OF COLORADO · PI WAGER, TOR D. · 2007 to 2023
$8.5M
Brain and Genetic Predictors of Individual Differences in Pain and Placebo AnalgesiaR01DA046064 · NIDA · UNIVERSITY OF COLORADO · PI FRIEDMAN, NAOMI P., WAGER, TOR D. · 2018 to 2022
$3.2M
fMRI-based Biomarkers for Multiple Components of PainR01DA035484 · NIDA · UNIVERSITY OF COLORADO · PI WAGER, TOR D. · 2013 to 2017
$3.1M
Neuroimaging-based biomarkers for two components of painRC1DA028608 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI SMITH, EDWARD E. · 2009 to 2010
$999k
Psychological and brain mechanisms underlying disparities in opioid and non-opioid pain treatment decisionsK01DA045735 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI LOSIN, ELIZABETH R · 2018 to 2022
$861k
NIDA NIH HHS K01 DA045735NIDA NIH HHS R01 DA035484NIDA NIH HHS R01 DA046064NIDA NIH HHS RC1 DA028608NIMH NIH HHS R01 MH076136
6 · The paper itself

Abstract

Caregiving and other interpersonal interactions often require accurate perception of others' pain from nonverbal cues, but perceivers may be subject to systematic biases based on gender, race, and other contextual factors. Such biases could contribute to systematic under-recognition and undertreatment of pain. In 2 experiments, we studied the impact of perceived patient sex on lay perceivers' pain estimates and treatment recommendations. In Experiment 1 (N = 50), perceivers viewed facial video clips of female and male patients in chronic shoulder pain and estimated patients' pain intensity. Multi-level linear modeling revealed that perceivers under-estimated female patients' pain compared with male patients, after controlling for patients' self-reported pain and pain facial expressiveness. Experiment 2 (N = 200) replicated these findings, and additionally found that 1) perceivers' pain-related gender stereotypes, specifically beliefs about typical women's vs. men's willingness to express pain, predicted pain estimation biases; and 2) perceivers judged female patients as relatively more likely to benefit from psychotherapy, whereas male patients were judged to benefit more from pain medicine. In both experiments, the gender bias effect size was on average 2.45 points on a 0-100 pain scale. Gender biases in pain estimation may be an obstacle to effective pain care, and experimental approaches to characterizing biases, such as the one we tested here, could inform the development of interventions to reduce such biases. Perspective: This study identifies a bias towards underestimation of pain in female patients, which is related to gender stereotypes. The findings suggest caregivers' or even clinicians' pain stereotypes are a potential target for intervention.

Indexed as

Chronic PainPain ManagementSexismShoulder PainSocial PerceptionStereotypingAdolescentAdultFemaleHumansMaleMiddle AgedVideo RecordingYoung Adultgender biaspain estimationpain-related gender role expectationpain treatment recommendationsSexstereotypes

Identifiers

PMID33684539
PMCPMC8827218
OpenAlexW3135617318

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.