Evidence map›Paper›PMID 33684519›Full record

ReviewMicrobes and infection

Anti-malarial humoral immunity: the long and short of it.

Kai J Rogers, Rahul Vijay, Noah S Butler

Abstract readReview
In one paragraph

Review in Microbes and infection. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. T follicular helper cell development during malaria.Current opinion in immunology · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. International journal for parasitology. Parasites and wildlife · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kai J RogersDepartment of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
Rahul VijayDepartment of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
Noah S ButlerDepartment of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA; Interdisciplinary Graduate Program in Immunology, The University of Iowa, Iowa City, IA, USA. Electronic address: noah-butler@uiowa.edu.

Funding

Regulation of Plasmodium-specific CD4+ T CellsR01AI127481 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Noah Sullivan Butler · 2016 to 2026
$3.8M
Development and function of CD4+ memory T cells during malariaR01AI125446 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Noah Sullivan Butler · 2016 to 2026
$3.7M
NIAID NIH HHS R01 AI125446NIAID NIH HHS R01 AI127481
6 · The paper itself

Abstract

Humoral immunity is critical for limiting Plasmodium parasite infections and the severity of malaria. Naturally acquired immunity against malaria occurs inefficiently and protection is relatively short-lived. Here we review recent advances and explore emerging hypotheses regarding the molecular and cellular pathways that regulate Plasmodium parasite-specific B cell responses and durable anti-malarial humoral immunity.

Indexed as

Immunity, HumoralHumansMalariaTime FactorsAntibodyMalariaMemory B cellMetabolismPlasmablastPlasma cell

Identifiers

PMID33684519
PMCPMC8292161

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.