Evidence map›Paper›PMID 33684453›Full record

ArticlePharmacology, biochemistry, and behavior2021

Prevalence and drug use correlates of extra-medical use of prescription medications for sleep among adults in the United States: Results of the 2015-2018 National Survey on Drug Use and Health.

Catalina Lopez-Quintero, Trey Warren, Alyssa Falise, Vinita Sharma, Cristina Bares, Assaf Oshri

Open access · greenAbstract read
In one paragraph

Article in Pharmacology, biochemistry, and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Catalina Lopez-QuinteroDepartment of Epidemiology, University of Florida, Gainesville, FL 32611, USA. Electronic address: catalinalopezqui@ufl.edu.
Trey WarrenDepartment of Epidemiology, University of Florida, Gainesville, FL 32611, USA. Electronic address: trey131@ufl.edu.
Alyssa FaliseDepartment of Epidemiology, University of Florida, Gainesville, FL 32611, USA. Electronic address: Alyssa.falise@ufl.edu.
Vinita SharmaDepartment of Epidemiology, University of Florida, Gainesville, FL 32611, USA. Electronic address: vinita.sharma@ufl.edu.
Cristina BaresSchool of Social Work, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: cbb@umich.edu.
Assaf OshriDepartment of Human Development and Family Science, College of Family and Consumer Sciences, University of Georgia, Athens, GA, 30602, USA. Electronic address: oshri@uga.edu.
University of Florida · USUniversity of Georgia · USUniversity of Michigan–Ann Arbor · US

Funding

UF Substance Abuse Training Center in Public HealthT32DA035167 · NIDA · UNIVERSITY OF FLORIDA · PI Linda B. Cottler · 2014 to 2026
$4.8M
The influence of community and family protective processes on neurocognitive systems associated with early-onset drug use: An investigation of rural southern youthK01DA045219 · NIDA · UNIVERSITY OF GEORGIA · PI OSHRI, ASSAF · 2018 to 2022
$889k
Drug use disparities among Hispanics: elucidating the complex interactions between socio-cultural, neurocognitive and drug use-related factorsK01DA046715 · NIDA · UNIVERSITY OF FLORIDA · PI LOPEZ-QUINTERO, CATALINA · 2018 to 2022
$763k
NIDA NIH HHS K01 DA045219NIDA NIH HHS K01 DA046715NIDA NIH HHS T32 DA035167
6 · The paper itself

Abstract

backgroundThis paper examines the epidemiology of extra-medical use of prescription medications for sleep among a nationally representative sample of U.S. adults.

methodsWe analyzed data from the 2015-2018 National Surveys on Drug Use and Health. The sample includes 3410 U.S. adults who reported extra-medical use of prescription medications for sleep. Multinomial logistic regression models identified correlates of type of drug used [i.e., sedatives and/or tranquilizers-only (ST-only), prescription pain relievers-only (PPR-only), or sedatives, tranquilizers, and prescription pain relievers (ST + PPR)], and logistic regression models identified correlates of reasons for extra-medical use (i.e., sleep-only vs. sleep and recreational).

resultsAbout 60% (95%CI = 58.9, 63.5) of the sample reported extra-medical use of ST-only, followed by PPR-only (29.9%, 95%CI = 27.5, 32.5), and ST + PPR (8.9%, 95%CI = 7.7, 10.4). Recreational use was reported by 28.4% (95% CI = 26.5, 30.4) of the sample. The odds of extra-medical use of PPR-only (aRRR = 3.1, 95%CI = 2.1, 4.5) and ST + PPR (aRRR = 1.9, 95%CI = 1.2, 3.1) as opposed to ST-only, were greater among Non-Hispanic Blacks than Non-Hispanic Whites. Compared to non-alcohol users, those with a past-12 months diagnosis of alcohol use disorder were more likely to use ST + PPR rather than ST-only (aIRR = 2.0, 95%CI = 1.1, 3.7). Non-Hispanic Blacks (aOR = 0.6, 95%CI = 0.4, 08) and individuals living in rural areas (aOR = 0.5, 95%CI = 0.3, 09) were less likely to report extra-medical use of prescription medications for recreational reasons than Non-Hispanic Whites and those residing in large metropolitan areas, respectively.

conclusionsExtra-medical use of PPR-only and ST + PPR as an aid to sleep, is prevalent among Non-Hispanic Blacks, young adults, and those residing in rural areas. Most individuals reported that extra-medical use of prescription medications was primarily motivated by sleep reasons, rather than by sleep and recreational reasons. Potential interventions include access to sleep treatments, education on the effectiveness and risk associated with extra-medical use and co-use of prescription medications for sleep, and research on sleep-related disparities.

Indexed as

AdolescentAdultAlcoholismAnalgesicsAnalgesics, OpioidDrug PrescriptionsFemaleHumansHypnotics and SedativesLogistic ModelsMaleMiddle AgedPrescription Drug MisusePrevalenceRecreational Drug UseSleepAnalgesicsAnalgesics, OpioidHypnotics and SedativesSleep Aids, PharmaceuticalTranquilizing AgentsMisuseOpioidsPain relieversSedativesSleepTranquilizers

Identifiers

PMID33684453
PMCPMC8409243
OpenAlexW3135580521

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.