Evidence map›Paper›PMID 33684290›Full record

ArticleJournal of the American Chemical Society2021

A Thioether-Ligated Cupric Superoxide Model with Hydrogen Atom Abstraction Reactivity.

Mayukh Bhadra, Wesley J Transue, Hyeongtaek Lim, Ryan E Cowley, Jung Yoon C Lee, Maxime A Siegler, Patrick Josephs, Gerald Henkel, Markus Lerch, Siegfried Schindler and 5 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 39 citations in OpenAlex.

  1. Mechanism of OACS central science · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Ligand-Copper(I) Primary OAccounts of chemical research · 2023
    Article
  6. Fenton-like Chemistry by a Copper(I) Complex and HJournal of the American Chemical Society · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Mayukh BhadraDepartment of Chemistry, The Johns Hopkins University, Baltimore, Maryland 21218, United States.ORCID 0000-0002-4758-1610
Wesley J TransueDepartment of Chemistry, Stanford University, Stanford, California 94305, United States.ORCID 0000-0001-7445-5663
Hyeongtaek LimDepartment of Chemistry, Stanford University, Stanford, California 94305, United States.ORCID 0000-0003-3470-8296
Ryan E CowleyDepartment of Chemistry, Stanford University, Stanford, California 94305, United States.ORCID 0000-0003-1791-4266
Jung Yoon C LeeDepartment of Chemistry, The Johns Hopkins University, Baltimore, Maryland 21218, United States.
Maxime A SieglerDepartment of Chemistry, The Johns Hopkins University, Baltimore, Maryland 21218, United States.ORCID 0000-0003-4165-7810
Patrick JosephsDepartment of Chemistry, University of Paderborn, Paderborn D-33098, Germany.
Gerald HenkelDepartment of Chemistry, University of Paderborn, Paderborn D-33098, Germany.
Markus LerchInstitute of Inorganic and Analytical Chemistry, Justus-Liebig University of Gießen, Giessen D-35392, Germany.
Siegfried SchindlerInstitute of Inorganic and Analytical Chemistry, Justus-Liebig University of Gießen, Giessen D-35392, Germany.
Adam NeubaDepartment of Chemistry, University of Paderborn, Paderborn D-33098, Germany.
Keith O HodgsonDepartment of Chemistry, Stanford University, Stanford, California 94305, United States.
Britt HedmanStanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Stanford University, Menlo Park, California 94025, United States.
Edward I SolomonDepartment of Chemistry, Stanford University, Stanford, California 94305, United States.ORCID 0000-0003-0291-3199
Kenneth D KarlinDepartment of Chemistry, The Johns Hopkins University, Baltimore, Maryland 21218, United States.ORCID 0000-0002-5675-7040
Johns Hopkins University · USPaderborn University · DESLAC National Accelerator Laboratory · USStanford University · USJustus-Liebig-Universität Gießen · DE

Funding

A Synchrotron Radiation Structural Biology ResourcesP30GM133894 · NIGMS · STANFORD UNIVERSITY · PI Clyde Smith · 2020 to 2026
$43.3M
Structure/Function Correlations Over Copper EnzymesR01DK031450 · NIDDK · STANFORD UNIVERSITY · PI EDWARD I SOLOMON · 1986 to 2026
$8.7M
Heme/Copper and Heme/Nonheme Iron O(2) and NO ReactivityR01GM060353 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI KARLIN, KENNETH D. · 2000 to 2020
$5.9M
SPECTROSCOPIC STUDIES OF COPPER CLUSTERS IN PROTEINSR37DK031450 · NIDDK · STANFORD UNIVERSITY · PI SOLOMON, EDWARD I · 1994 to 2011
$5.7M
Oxygen Activation by Mononuclear Copper(I) Active SitesF32GM131602 · NIGMS · STANFORD UNIVERSITY · PI TRANSUE, WESLEY JOHN · 2019 to 2022
$221k
NIDDK NIH HHS R01 DK031450NIDDK NIH HHS R37 DK031450NIGMS NIH HHS F32 GM131602NIGMS NIH HHS P30 GM133894NIGMS NIH HHS R01 GM060353
6 · The paper itself

Abstract

The central role of cupric superoxide intermediates proposed in hormone and neurotransmitter biosynthesis by noncoupled binuclear copper monooxygenases like dopamine-β-monooxygenase has drawn significant attention to the unusual methionine ligation of the Cu

Indexed as

CopperDensity Functional TheoryHydrogenKineticsMolecular ConformationOxidation-ReductionSpectrophotometry, UltravioletSulfidesSuperoxidesCopperHydrogenSulfidesSuperoxides

Identifiers

PMID33684290
PMCPMC8023764
OpenAlexW3134167129

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.