Evidence map›Paper›PMID 33684174›Full record

ArticlePloS one2021

Rhabdomyolysis among hospitalized patients for salicylate intoxication in the United States: Nationwide inpatient sample 2003-2014.

Wisit Kaewput, Charat Thongprayoon, Tananchai Petnak, Wisit Cheungpasitporn, Fawad Qureshi, Boonphiphop Boonpheng, Saraschandra Vallabhajosyula, Tarun Bathini, Sohail Abdul Salim, Tibor Fülöp

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Wisit KaewputDepartment of Military and Community Medicine, Phramongkutklao College of Medicine, Bangkok, Thailand.ORCID 0000-0003-2920-7235
Charat ThongprayoonDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States of America.
Tananchai PetnakDivision of Pulmonary and Critical Care Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Wisit CheungpasitpornDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States of America.
Fawad QureshiDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States of America.
Boonphiphop BoonphengDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States of America.
Saraschandra VallabhajosyulaSection of Interventional Cardiology, Division of Cardiovascular Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Tarun BathiniDepartment of Internal Medicine, University of Arizona, Tucson, Arizona, United States of America.
Sohail Abdul SalimDivision of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America.
Tibor FülöpDepartment of Internal Medicine, Division of Nephrology, Medical University of South Carolina, Charleston, South Carolina, United States of America.
Mayo Clinic · USEmory University · USMedical University of South Carolina · USPhramongkutklao Hospital · THUniversity of Arizona · USUniversity of California, Los Angeles · USUniversity of Mississippi Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aimed to assess the risk factors and impact of rhabdomyolysis on treatments, outcomes, and resource utilization in hospitalized patients for salicylate intoxication in the United States. MATERIALS AND

methodsThe National Inpatient Sample was utilized to identify hospitalized patients with a primary diagnosis of salicylate intoxication from 2003-2014. Rhabdomyolysis was identified using hospital diagnosis code. We compared the clinical characteristics, in-hospital treatment, outcomes, and resource utilization between patients with and without rhabdomyolysis.

resultsA total of 13,805 hospital admissions for salicylate intoxication were studied. Of these, rhabdomyolysis developed in 258 (1.9%) admissions. The risk factors for rhabdomyolysis were age>20 years, male sex, volume depletion, hypokalemia, sepsis, and seizure. After adjustment for baseline clinical characteristics, salicylate intoxication patients with rhabdomyolysis required more invasive mechanical ventilation, and renal replacement therapy. Rhabdomyolysis was significantly associated with higher risk of failure of any organ systems, and in-hospital mortality. Length of hospital stay and hospitalization cost were higher when rhabdomyolysis occurred during hospital stay.

conclusionsRhabdomyolysis was not common in hospitalized patients for salicylate intoxication but it was associated with increased morbidity, mortality, and resource utilization.

Indexed as

Databases, FactualLength of StayRenal Replacement TherapyRhabdomyolysisAdultFemaleHumansMaleMiddle AgedRisk FactorsSalicylatesUnited StatesSalicylates

Identifiers

PMID33684174
PMCPMC7939294
OpenAlexW3134208130

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.