Evidence map›Paper›PMID 33683982›Full record

ArticleXenobiotica; the fate of foreign compounds in biological systems2021

Disposition and metabolism of ethylene glycol 2-ethylhexyl ether in Sprague Dawley rats, B6C3F1/N mice, and

AtLee T D Watson, Benjamin C Moeller, Melanie Doyle-Eisele, Edwin Garner, Chad R Blystone, Jacob D McDonald, Suramya Waidyanatha

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Xenobiotica; the fate of foreign compounds in biological systems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

AtLee T D WatsonNational Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Benjamin C MoellerLovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA.
Melanie Doyle-EiseleLovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA.
Edwin GarnerLovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA.
Chad R BlystoneDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Jacob D McDonaldLovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA.
Suramya WaidyanathaNational Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Mental Research Institute · USNational Institute of Environmental Health Sciences · USTriangle · US

Funding

Toxicological Assessments for the National Toxicology ProgramZIAES103316 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WALKER, NIGEL J · 2016 to 2019
$31.9M
Toxicological Assessments for the Division of the National Toxicology ProgramZICES103316 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WALKER, NIGEL J · 2020 to 2021
$18.5M
Intramural NIH HHS ZIA ES103316NIEHS NIH HHS HHSN291200775562C
6 · The paper itself

Abstract

Ethylene glycol 2-ethylhexyl ether (EGEHE) is a solvent used in a variety of applications.We report disposition and metabolism of EGEHE following a single gavage or dermal administration of 50, 150 or 500 mg/kg [

Indexed as

Ethylene GlycolsHepatocytesAdministration, OralAnimalsEthersFemaleMaleMiceRatsRats, Sprague-DawleyTissue DistributionEthersEthylene Glycolsabsorptionalkoxyacetic aciddistributionEGEHEEthylene glycol 2-ethylhexyl etherexcretionglycol ethermetabolism

Identifiers

PMID33683982
PMCPMC8312400
OpenAlexW3135895135

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.