ArticleAging clinical and experimental research2021
Adverse cardiovascular magnetic resonance phenotypes are associated with greater likelihood of incident coronavirus disease 2019: findings from the UK Biobank.
Article in Aging clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Individual risk factors associated with SARS-CoV-2 infection during Alpha variant in high-income countries: a systematic review and meta-analysis.Frontiers in public health · 2024Pooled it
- Cardiac involvement in coronavirus disease 2019 assessed by cardiac magnetic resonance imaging: a meta-analysis.Heart and vessels · 2022Pooled it
- Cardiac Magnetic Resonance Imaging Findings in 2954 COVID-19 Adult Survivors: A Comprehensive Systematic Review.Journal of magnetic resonance imaging : JMRI · 2022Pooled it
- Impact of self-reported SARS-CoV-2 antibody positivity on cardiac structure and function: findings from UK Biobank CMR cohort.Frontiers in cardiovascular medicine · 2025Article
- Prospective electrocardiographic and cardiovascular magnetic resonance alterations in the UK Biobank coronavirus disease 2019 repeat imaging study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025Article
- Association of COVID-19 and Arterial Stiffness Assessed using Cardiovascular Index (CAVI).Current hypertension reviews · 2024Article
- The Impact of COVID-19 on Carotid-Femoral Pulse Wave Velocity: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- Cardiovascular Health Care Implications of the COVID-19 pandemic.Heart failure clinics · 2023Review
- Cardiovascular magnetic resonance for evaluation of cardiac involvement in COVID-19: recommendations by the Society for Cardiovascular Magnetic Resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Review
- Phenotyping myocardial injury related to COVID and SARS-CoV-2 vaccination: insights from cardiovascular magnetic resonance.Frontiers in cardiovascular medicine · 2023Article
- Photoplethysmographic Measurement of Arterial Stiffness in Polish Patients with Long-COVID-19 Syndrome-The Results of a Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2022Article
- Cardiovascular Health Care Implications of the COVID-19 pandemic.Cardiology clinics · 2022Review
- Acute and Long-Term Consequences of COVID-19 on Arterial Stiffness-A Narrative Review.Life (Basel, Switzerland) · 2022Review
- Cardiovascular Magnetic Resonance for Patients With COVID-19.JACC. Cardiovascular imaging · 2022Review
- The pathological maelstrom of COVID-19 and cardiovascular disease.Nature cardiovascular research · 2022Review
- The Pathogenesis and Long-Term Consequences of COVID-19 Cardiac Injury.JACC. Basic to translational science · 2022Review
- Cardiac Performance and Cardiopulmonary Fitness After Infection With SARS-CoV-2.Frontiers in cardiovascular medicine · 2022Article
- Day-to-day blood pressure variability and severity of COVID-19: Is sympathetic overdrive a potential link?Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Arterial stiffness and COVID-19: A bidirectional cause-effect relationship.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Physiological Role and Use of Thyroid Hormone Metabolites - Potential Utility in COVID-19 Patients.Frontiers in endocrinology · 2021Review
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundCoronavirus disease 2019 (COVID-19) disproportionately affects older people. Observational studies suggest indolent cardiovascular involvement after recovery from acute COVID-19. However, these findings may reflect pre-existing cardiac phenotypes.
aimsWe tested the association of baseline cardiovascular magnetic resonance (CMR) phenotypes with incident COVID-19.
methodsWe studied UK Biobank participants with CMR imaging and COVID-19 testing. We considered left and right ventricular (LV, RV) volumes, ejection fractions, and stroke volumes, LV mass, LV strain, native T1, aortic distensibility, and arterial stiffness index. COVID-19 test results were obtained from Public Health England. Co-morbidities were ascertained from self-report and hospital episode statistics (HES). Critical care admission and death were from HES and death register records. We investigated the association of each cardiovascular measure with COVID-19 test result in multivariable logistic regression models adjusting for age, sex, ethnicity, deprivation, body mass index, smoking, diabetes, hypertension, high cholesterol, and prior myocardial infarction.
resultsWe studied 310 participants (n = 70 positive). Median age was 63.8 [57.5, 72.1] years; 51.0% (n = 158) were male. 78.7% (n = 244) were tested in hospital, 3.5% (n = 11) required critical care admission, and 6.1% (n = 19) died. In fully adjusted models, smaller LV/RV end-diastolic volumes, smaller LV stroke volume, and poorer global longitudinal strain were associated with significantly higher odds of COVID-19 positivity. DISCUSSION: We demonstrate association of pre-existing adverse CMR phenotypes with greater odds of COVID-19 positivity independent of classical cardiovascular risk factors.
conclusionsObservational reports of cardiovascular involvement after COVID-19 may, at least partly, reflect pre-existing cardiac status rather than COVID-19 induced alterations.
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Registered trials
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