ReviewAmerican journal of clinical dermatology2021
Erythema Nodosum: A Practical Approach and Diagnostic Algorithm.
Review in American journal of clinical dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed, 126 citations in OpenAlex.
- Drug and Vaccine-Associated Erythema Nodosum: Insights From the FAERS and VAERS Database.The Australasian journal of dermatology · 2026Article
- Article
- Article
- YouTube as a source of patient information on erythema nodosum: an analysis of quality and reliability.Clinical rheumatology · 2026Article
- Article
- [Differential diagnoses: skin changes on the leg and their significance].Dermatologie (Heidelberg, Germany) · 2026Article
- Necrobiosis Lipoidica in Pregnancy Complicated by Gestational Diabetes Mellitus: A Case Report.Cureus · 2026Article
- Pediatric Plantar Erythema Nodosum Associated with Beta-Hemolytic Streptococcal Infection: A Rare condition.Dermatology practical & conceptual · 2026Article
- The overlooked surface: cutaneous manifestations of inflammatory bowel disease.Translational gastroenterology and hepatology · 2026Review
- Recurrent Erythema Nodosum Associated With Finger Millet-Blended Injera: A Case Report on a Potential Dietary Trigger.Clinical case reports · 2025Article
- Gut-skin axis: Emerging insights for gastroenterologists-a narrative review.World journal of gastrointestinal pathophysiology · 2025Review
- Fatal case of pancreatic panniculitis and polyarthritis due to pancreatic neuroendocrine tumor: a case report and review of literature.Rheumatology international · 2025Review
- Article
- Panniculitis: a narrative review.Archives of dermatological research · 2025Review
- [Erythema nodosum].Dermatologie (Heidelberg, Germany) · 2025Article
- Editorial: Advances in skin immunology.Frontiers in immunology · 2025Article
- Article
- Review
- Exploring the connection between hidradenitis suppurativa and erythema nodosum: a case report.Dermatology reports · 2024Article
- Erythema nodosum as first clinical manifestation of metastatic neuroendocrine tumor: A case report.Heliyon · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy. We propose a diagnostic algorithm to optimize the initial work-up, hence initiating prompt and accurate management of the underlying disease. The algorithm includes an initial assessment of core symptoms, diagnostic work-up, differential diagnosis, and recommended therapies. Several treatment options for the erythema nodosum lesions have been previously reported; nevertheless, these options treat the symptoms, but not the triggering cause. Making an accurate diagnosis will allow the physician to treat the underlying cause and determine an optimal therapeutic strategy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.