Evidence map›Paper›PMID 33683548›Full record

ArticleSleep & breathing = Schlaf & Atmung2021

Tidal volume and stroke volume changes caused by respiratory events during sleep and their relationship with OSA severity: a pilot study.

Oh Eun Kwon, Kyung Hun Shin, Thi Hang Dang, Hyo Je Ahn, Eui Hyeok Rhie, Geuk Young Jang, Tong In Oh, Yongmin Kim, Sung Wan Kim, Eung Je Woo

Abstract read
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Oh Eun KwonDepartment of Otorhinolaryngology - Head & Neck Surgery, Kangdong Sacred Heart Hospital, Seoul, South Korea.
Kyung Hun ShinDepartment of Biomedical Engineering, School of Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea.
Thi Hang DangDepartment of Biomedical Engineering, School of Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea.
Hyo Je AhnDepartment of Biomedical Engineering, School of Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea.
Eui Hyeok RhieDepartment of Neuroscience Lab, Kyung Hee University Medical Center, Seoul, South Korea.
Geuk Young JangDepartment of Biomedical Engineering, School of Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea.
Tong In OhDepartment of Biomedical Engineering, School of Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea.
Yongmin KimDepartment of Creative IT Engineering, POSTECH, Pohang, South Korea.
Sung Wan KimDepartment of Otorhinolaryngology - Head & Neck Surgery, School of Medicine, Kyung Hee University, Seoul, South Korea.
Eung Je WooDepartment of Biomedical Engineering, School of Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea. ejwoo@khu.ac.kr.ORCID 0000-0001-5100-6945

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBreath-by-breath tidal volume (TV) and beat-by-beat stroke volume (SV) were continuously measured in patients with OSA undergoing polysomnography (PSG). The objectives were to (1) determine the changes in TV/SV in response to respiratory events and (2) assess the relationship between these changes and the disease severity.

methodsFrom the PSG data of nine patients with OSA, six different types of respiratory events were identified, i.e., flow limitation (FL), respiratory effort related arousal (RERA), hypopnea with arousal only (Ha), hypopnea with desaturation only (Hd), hypopnea with arousal and desaturation (Had), and apnea. The measured TV and SV values during and after each respiratory event were compared with the pre-event baseline values.

resultsThe mean TV/SV reductions during all hypopneas and apneas were 38.1%/4.2% and 70.5%/8.8%, respectively. Among three different hypopnea types, the reductions in TV during Hd and Had were significantly greater than those during Ha. The TV reductions during Ha and FL were similar. After RERA, Ha, Had, and apnea, there was an overshoot in TV and SV values, whereas there was no overshoot after FL and Hd. During RERA, there was no reduction in TV/SV.

conclusionsThe changes in TV during and after each type of respiratory event were significantly different in most cases. The changes in SV between hypopnea and apnea were different with statistical significance. The AHI does not properly account for the ventilation losses caused by respiratory events. Thus, TV measurements might be useful in the future in assessing the OSA severity in conjunction with the AHI.

Indexed as

AdultFemaleHumansMaleMiddle AgedPatient AcuityPilot ProjectsPolysomnographySleep Apnea, ObstructiveStroke VolumeTidal VolumeElectrical impedance tomographyObstructive sleep apneaPolysomnographyStroke volumeTidal volume

Identifiers

PMID33683548

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.