Evidence map›Paper›PMID 33683542›Full record

ArticleLa Radiologia medica2021

Volumetric histograms-based analysis of apparent diffusion coefficients and standard uptake values for the assessment of pediatric sarcoma at staging: preliminary results of a PET/MRI study.

Giovanna Orsatti, Pietro Zucchetta, Alessia Varotto, Filippo Crimì, Michael Weber, Diego Cecchin, Gianni Bisogno, Alessandro Spimpolo, Chiara Giraudo, Roberto Stramare

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Article in La Radiologia medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Giovanna OrsattiDepartment of Medicine - DIMED, Institute of Radiology, Padova University, Via Giustiniani 2, 35100, Padua, Italy.
Pietro ZucchettaNuclear Medicine Unit, Department of Medicine - DIMED, University of Padova, Padua, Italy.
Alessia VarottoNeuroradiology Unit, San Bortolo Hospital, Vicenza, Italy.
Filippo CrimìDepartment of Medicine - DIMED, Institute of Radiology, Padova University, Via Giustiniani 2, 35100, Padua, Italy.
Michael WeberDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Diego CecchinNuclear Medicine Unit, Department of Medicine - DIMED, University of Padova, Padua, Italy.
Gianni BisognoHematology and Oncology Division, Department of Women's and Children's Health, University of Padova, Padua, Italy.
Alessandro SpimpoloNuclear Medicine Unit, Department of Medicine - DIMED, University of Padova, Padua, Italy.
Chiara GiraudoDepartment of Medicine - DIMED, Institute of Radiology, Padova University, Via Giustiniani 2, 35100, Padua, Italy. chiara.giraudo@unipd.it.ORCID http://orcid.org/0000-0003-0924-5883
Roberto StramareDepartment of Medicine - DIMED, Institute of Radiology, Padova University, Via Giustiniani 2, 35100, Padua, Italy.
University of Padua · ITMedical University of Vienna · ATOspedale San Bortolo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the relationship between apparent diffusion coefficients (ADC) and standard uptake values (SUV) of pediatric sarcomas at staging by using volumetric histograms analyses.

methodsChildren with histologically proven sarcoma, referring to our tertiary center for a whole-body

resultsThirteen patients met the inclusion criteria (six females; mean age 8.31 ± 6.03 years). Histology revealed nine rhabdomyosarcomas, three Ewing sarcomas, and one chondroblastic osteosarcoma. A significant negative correlation between ADCs' and SUVs' mean (r

conclusionOur preliminary results demonstrate that, using volumetric histograms, simultaneously collected SUVs and ADCs are dependent biomarkers in pediatric FDG-avid sarcomas. Further studies, on a larger population, are necessary to confirm this evidence and assess its clinical implications.

Indexed as

Bone NeoplasmsChildFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMalePositron-Emission TomographyRetrospective StudiesSarcomaADCHistogramsPediatric sarcomaPET/MRISUV

Identifiers

PMID33683542
OpenAlexW3133654117

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.