ArticleHuman brain mapping2021
Mapping of multiple muscles with transcranial magnetic stimulation: absolute and relative test-retest reliability.
Article in Human brain mapping, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Quantitative Navigated Transcranial Magnetic Stimulation Motor Mapping and nTMS-Guided Corticospinal Tractography in Healthy Individuals and Patients with Motor-Eloquent Brain Tumors.Brain sciences · 2026Article
- GABAergic and glutamatergic mechanisms of cortical excitability shape motor resonance during action observation as measured by transcranial magnetic stimulation.Frontiers in human neuroscience · 2026Article
- On the Relation Between the Interstimulus Intervals and Multi-Muscle nTMS Motor Mapping.Brain topography · 2025Article
- Optimising Paediatric Brain Mapping with Single-Pulse Transcranial Magnetic Stimulation: A New Protocol and Insights.Annals of neurosciences · 2025Article
- Efficient prospective electric field-informed localization of motor cortical targets of transcranial magnetic stimulation.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- The reliability and validity of rapid transcranial magnetic stimulation mapping for muscles under active contraction.BMC neuroscience · 2024Article
- Sub-concussive head impacts from heading footballs do not acutely alter brain excitability as compared to a control group.PloS one · 2024Article
- Overlap in the cortical representation of hand and forearm muscles as assessed by navigated TMS.Neuroimage. Reports · 2023Article
- MarLe: Markerless estimation of head pose for navigated transcranial magnetic stimulation.Physical and engineering sciences in medicine · 2023Article
- Mapping Brain Motor Functions Using Transcranial Magnetic Stimulation with a Volume Conductor Model and Electrophysiological Experiments.Brain sciences · 2023Article
- Transcranial magnetic stimulation mapping of the motor cortex: comparison of five estimation algorithms.Frontiers in neuroscience · 2023Article
- Multi-scale and cross-dimensional TMS mapping: A proof of principle in patients with Parkinson's disease and deep brain stimulation.Frontiers in neuroscience · 2023Article
- Semi-automated motor hotspot search (SAMHS): a framework toward an optimised approach for motor hotspot identification.Frontiers in human neuroscience · 2023Article
- Forearm and Hand Muscles Exhibit High Coactivation and Overlapping of Cortical Motor Representations.Brain topography · 2022Article
- Accounting for Stimulations That Do Not Elicit Motor-Evoked Potentials When Mapping Cortical Representations of Multiple Muscles.Frontiers in human neuroscience · 2022Article
- Towards more reliable TMS studies - How fast can we probe cortical excitability?Clinical neurophysiology practice · 2022Article
- Capturing Neuroplastic Changes after iTBS in Patients with Post-Stroke Aphasia: A Pilot fMRI Study.Brain sciences · 2021Article
- Mapping of Motor Function with Neuronavigated Transcranial Magnetic Stimulation: A Review on Clinical Application in Brain Tumors and Methods for Ensuring Feasible Accuracy.Brain sciences · 2021Review
- Mapping of multiple muscles with transcranial magnetic stimulation: absolute and relative test-retest reliability.Human brain mapping · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The spatial accuracy of transcranial magnetic stimulation (TMS) may be as small as a few millimeters. Despite such great potential, navigated TMS (nTMS) mapping is still underused for the assessment of motor plasticity, particularly in clinical settings. Here, we investigate the within-limb somatotopy gradient as well as absolute and relative reliability of three hand muscle cortical representations (MCRs) using a comprehensive grid-based sulcus-informed nTMS motor mapping. We enrolled 22 young healthy male volunteers. Two nTMS mapping sessions were separated by 5-10 days. Motor evoked potentials were obtained from abductor pollicis brevis (APB), abductor digiti minimi, and extensor digitorum communis. In addition to individual MRI-based analysis, we studied normalized MNI MCRs. For the reliability assessment, we calculated intraclass correlation and the smallest detectable change. Our results revealed a somatotopy gradient reflected by APB MCR having the most lateral location. Reliability analysis showed that the commonly used metrics of MCRs, such as areas, volumes, centers of gravity (COGs), and hotspots had a high relative and low absolute reliability for all three muscles. For within-limb TMS somatotopy, the most common metrics such as the shifts between MCR COGs and hotspots had poor relative reliability. However, overlaps between different muscle MCRs were highly reliable. We, thus, provide novel evidence that inter-muscle MCR interaction can be reliably traced using MCR overlaps while shifts between the COGs and hotspots of different MCRs are not suitable for this purpose. Our results have implications for the interpretation of nTMS motor mapping results in healthy subjects and patients with neurological conditions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.