Evidence map›Paper›PMID 33682957›Full record

ArticleDrug and alcohol review2021

Impact of body mass and alcohol consumption on all-cause and liver mortality in 240 000 adults in the United States.

Jayadeep Patra, Charlotte Buckley, William C Kerr, Alan Brennan, Robin C Purshouse, Jürgen Rehm

Abstract read
In one paragraph

Article in Drug and alcohol review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Pathogenesis of Alcohol-Associated Liver Disease.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jayadeep PatraInstitute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Canada.ORCID 0000-0002-5666-2711
Charlotte BuckleyDepartment of Automatic Control and Systems Engineering, University of Sheffield, Sheffield, UK.ORCID 0000-0002-8430-0347
William C KerrAlcohol Research Group, Public Health Institute, Emeryville, CA, USA.ORCID 0000-0001-6612-9200
Alan BrennanSchool of Health and Related Research, University of Sheffield, Sheffield, UK.
Robin C PurshouseDepartment of Automatic Control and Systems Engineering, University of Sheffield, Sheffield, UK.
Jürgen RehmInstitute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Canada.ORCID 0000-0001-5665-0385

Funding

Calibrated Agent Simulations for Combined Analysis of Drinking Etiologies (CASCADE)R01AA024443 · NIAAA · UNIVERSITY OF SHEFFIELD · PI PURSHOUSE, ROBIN · 2016 to 2020
$2.3M
NIAAA NIH HHS R01 AA024443NIAAA NIH HHS R01AA024443
6 · The paper itself

Abstract

introductionNationally representative studies of the combined impact of drinking and body mass (BMI) on mortality outcomes are unavailable. We investigate whether both act together to elevate risk of all-cause or liver mortality.

methodsWe obtained self-reported histories of drinking and BMI from 129 098 women (mean age 47.2 years) and 102 568 men (mean age 45.6 years) ≥18 years interviewed from 1997 to 2004 in the National Health Interview Survey and related these data to the deaths that occurred by 31 December 2006 (women = 8486; men = 7819 deaths). Death hazards among current drinkers in different BMI groups were adjusted for age, education, race and smoking.

resultsObese (≥30 kg m DISCUSSION AND

conclusionsObesity and excess alcohol are both related to all-cause and liver mortality-the latter with evidence of a supra-additive interaction between the risk factors. The presence of both factors in the same population and their impact should inform treatment, public health policies and research.

Indexed as

Alcohol DrinkingObesityAdultBody Mass IndexFemaleHumansLiverMaleMiddle AgedRisk FactorsUnited Statesheavy drinkinghigh body mass indexinteraction effectNational Health Interview Surveyobesity

Identifiers

PMID33682957
PMCPMC9383267

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.