Evidence map›Paper›PMID 33682859›Full record

ArticleJournal of visualized experiments : JoVE2021

Creating Avian Forebrain Chimeras to assess Facial Development.

Diane Hu, Ralph S Marcucio

Open access · greenAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Diane HuDepartment of Orthopaedic Surgery, Orthopaedic Trauma Institute, University of California.
Ralph S MarcucioDepartment of Orthopaedic Surgery, Orthopaedic Trauma Institute, University of California; Ralph.marcucio@ucsf.edu.
Orthopaedic Trauma Association · US

Funding

The role of continuous phenotypic variation in structural defects of the faceR01DE019638 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Benedikt Hallgrimsson, Ralph S Marcucio · 2010 to 2026
$7.3M
MOLECULAR BASIS OF TISSUE INTERACTIONS THAT REGULATE CRANIOFACIAL DEVELOPMENTR01DE018234 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARCUCIO, RALPH S · 2007 to 2017
$3.5M
NIDCR NIH HHS R01 DE018234NIDCR NIH HHS R01 DE019638
6 · The paper itself

Abstract

The avian embryo has been used as a model system for more than a century and has led to fundamental understanding of vertebrate development. One of the strengths of this model system is that the effect of, and interaction among, tissues can be directly assessed in chimeric embryos. We have previously shown that signals from the forebrain contribute to facial morphogenesis by regulating the shape of the expression domain of Sonic hedgehog (SHH) in the Frontonasal Ectodermal Zone (FEZ). In this article, the method of generating the forebrain chimeras and provide illustrations of the outcomes of these experiments is described.

Indexed as

AnimalsBirdsChickensChimeraCoturnixDucksEmbryo, NonmammalianFace

Identifiers

PMID33682859
PMCPMC8628319
OpenAlexW3131507050

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.